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Stable laser-acceleration of high-flux proton beams with plasma collimation.
Nat Commun
January 2025
School of Mathematics and Physics, Queen's University Belfast, Belfast, UK.
Laser-plasma acceleration of protons offers a compact, ultra-fast alternative to conventional acceleration techniques, and is being widely pursued for potential applications in medicine, industry and fundamental science. Creating a stable, collimated beam of protons at high repetition rates presents a key challenge. Here, we demonstrate the generation of multi-MeV proton beams from a fast-replenishing ambient-temperature liquid sheet.
View Article and Find Full Text PDFPerceptions From Non-Magnet® Organizations: Nurse Leaders' Transformational Leadership Behaviors and Clinical Nurses' Structural Empowerment.
J Nurs Adm
February 2025
Author Affiliation: Director of Nursing, Inpatient, Perinatal, and Emergency Services, Mount Auburn Hospital, Cambridge, Massachusetts.
Objective: The aim of this study was to investigate the correlation between nurse leaders' transformational leadership and clinical nurses' structural empowerment in non-Magnet® hospitals, and the differences in this correlation by Magnet status.
Background: Nurse leaders' transformational leadership has been positively correlated to increased structural empowerment in clinical nurses, primarily in Magnet-designated hospitals and those pursuing Magnet designation.
Methods: A descriptive correlational study design was used to investigate the study aim.
Navigating the neurovascular maze of trigeminal neuralgia.
Radiol Case Rep
March 2025
Department of Psychiatry, Datta Meghe Institute of Medical Sciences, Sawangi, Wardha, Maharashtra 442001, India.
Tic douloureux, also known as trigeminal neuralgia, is distinguished by recurrent episodes of severe, lancinating pain that affects one or more branches of the trigeminal nerve, representing a prevalent pain syndrome. This condition has an annual incidence rate of 27 per 100,000 individuals. Nevertheless, direct compression caused by vertebrobasilar dolichoectasia (VBD) represents a considerably less frequent etiology of trigeminal neuralgia, with an estimated overall incidence of about 1%.
View Article and Find Full Text PDFKeyhole decompression surgery for holospinal epidural abscess: a novel approach for spinal stability preservation.
Eur Spine J
January 2025
Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan.
Purpose: Spinal epidural abscesses are rare yet serious conditions, often necessitating emergency surgical intervention. Holospinal epidural abscesses (HEA) extending from the cervical to the lumbosacral spine are even rarer and present significant challenges in management. This report aims to describe a case of HEA with both ventrally-located cervical and dorsally-located thoracolumbar epidural abscesses treated with a combination of anterior keyhole decompression and posterior skip decompression surgeries.
View Article and Find Full Text PDFA critical analysis of the potential of iron heterobimetallic complexes in anticancer research.
J Inorg Biochem
March 2025
Centro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal.
Due to their diverse chemical properties and high ability to interact with biological molecules and cellular processes, transition metal-based compounds have emerged as promising candidates for cancer therapy. Iron complexes are among them, however, there is a gap in the comprehensive analysis of heterometallic iron complexes in the anticancer field. This review aims to fill this gap by summarizing recent progress in the study of Fe(II) and Fe(III) heterobimetallic complexes for anticancer applications and to gather important insights and future perspectives, with special emphasis on their theranostic capabilities.
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