Instituto de Óptica, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Published: December 2012
AI Article Synopsis
Article Abstract
The aim of this work was to study, using numerical simulations, the attainable level of accuracy to reconstruct the wavefront aberrations from tangential refractive power data measured with dynamic skiascopy. Two mathematical methods have been implemented. The first one is based on curve integration of the curvature data, previously interpolated with cubic splines. The second one reconstructs the three-dimensional wavefront surface, represented by a Zernike polynomial expansion, using a two-step least-squares method. The different factors affecting the reconstruction--noise, sampling, and wavefront patterns--were quantified. The results provide useful information to design more efficient experimental setups based on spatial dynamic skiascopy.
Purpose: The purpose is to compare visual parameters between normal and amblyopic eyes in anisometropic amblyopia and to find predictive factors for occlusion therapy.
Methods: Sixty patients with anisometropic amblyopia between the ages of 5 and 25 years were enrolled in the prospective, longitudinal, and interventional study. Patients were selected based on no improvement with spectacle correction alone after 1 month of follow-up.
- The study focused on how chick retinal pigment epithelium (RPE) gene expression of BMPs (Bone Morphogenetic Proteins) changes during recovery after short-term optical treatments, including lens wear and form deprivation.
- White-Leghorn chicks were subjected to different lenses or diffusers for various durations, and then their recovery was monitored in terms of refractive errors and changes in choroidal thickness (ChT) over 96 hours.
- Key findings indicated that BMP2 gene expression significantly increased with +10 D lens treatment shortly after application, while -10 D and form deprivation treatments led to a decrease in BMP2 expression, with recovery times being notably different between treatments.
Purpose: Previous research has shown that accommodation deficits are common in individuals with Down syndrome (DS), but the origin and mechanisms behind these deficits are still unknown. The aim of this study was to investigate the characteristics of different ocular structures involved in accommodation, in particular the ciliary muscle (CM), in a population of individuals with DS to further understand this deficit and its mechanisms.
Methods: Thirty-two volunteer participants of pre-presbyopic age with (n = 16) and without DS (n = 16) were recruited.
Significance: A variety of subjective and objective procedures are available to measure the amplitude of accommodation. However, it is unclear whether the standard criterion of Hofstetter's minimum minus 2 D can be used to diagnose accommodative insufficiency with each of these techniques.
Purpose: The use of objective dynamic retinoscopy and three subjective techniques to diagnosis accommodative insufficiency was examined.
