Nanogels of a binary system of carboxymethyl chitosan (CMCh) and poly- (vinyl alcohol) PVA, were successfully synthesized by a novel in situ process. They were also characterized by various analytical tools like Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and X-ray diffraction (XRD). They were studied for their unique swelling properties in water and different pH solutions. They were also investigated for their great ability to capture or isolate bacteria and fungi from aquatic environments.
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http://dx.doi.org/10.3390/molecules18010190 | DOI Listing |
Int J Biol Macromol
December 2024
Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China. Electronic address:
A stimuli-responsive drug delivery system is developed for controlled delivery of curcumin (Cur) and chemo-photothermal therapy of breast cancer (BC). Cur is first loaded into mesoporous polydopamine nanoparticles (mPDA NPs) by π-π stacking, and then the Cur loaded mPDA NPs (mPDA NPs@Cur) are encapsulated in the hydrogels prepared through the crosslinking of oxidized konjac glucomannan (oxKGM) and carboxymethyl chitosan (CMCS). Owing to the pH-sensitivity of the hydrogels and the outstanding photothermal conversion capability of mPDA NPs, the release of Cur from the hydrogels can be greatly accelerated in acidic media upon near infrared (NIR) irradiation.
View Article and Find Full Text PDFJ Colloid Interface Sci
December 2024
Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, PR China. Electronic address:
The management of diabetic wounds (DW) is a significant challenge within the medical field. Effectively regulating the levels of reactive oxygen species (ROS) at the wound site and orchestrating the inflammatory response are effective strategies for DW treatment. In this study, a novel hydrogel was developed by cross-linking polyboronic acid-modified carboxymethyl chitosan with herbal active ingredient rosmarinic acid (RA), an active herbal ingredient, through dynamic boronic esters formation.
View Article and Find Full Text PDFInt J Nanomedicine
December 2024
Shanxi Medical University School and Hospital of Stomatology; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Taiyuan, Shanxi, 030001, People's Republic of China.
Purpose: During fixed orthodontic treatment, oral hygiene is difficult to ensure and can easily lead to an imbalance in the oral micro-ecological balance. In this study, based on the adhesive properties of polydopamine (PDA) and the good antimicrobial and remineralization properties of carboxymethyl chitosan (CMC) and xylitol (Xy), new nanocomposites with both antimicrobial and remineralization capabilities were prepared to coat on orthodontic brackets.
Methods: Composite carbon dots (CDs) were synthesized using carboxymethyl chitosan and xylitol, we characterized them and the antimicrobial properties of the CMC-Xy-CDs were investigated by co-cultivation with S.
Int J Biol Macromol
December 2024
Department of Materials Science and Engineering, Faculty of Engineering & Technology, Tarbiat Modares Universirty, Tehran, Iran.
One of the most effective ways to solve the problems caused by the presence of steel implants in the body is to apply a coating to them. This study aims to develop and optimize composite coatings of magnesium oxide (MgO), 58S bioactive glass (BG), and N-carboxymethyl chitosan (N-CMC) on stainless steel (SS316L) substrates using the electrophoretic deposition (EPD) method. The synthesized materials were characterized using FTIR, XRD, and SEM to confirm their structure and morphology prior to coating.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
National Science and Technology Development Agency (NSTDA), 111 Thailand Science Park, Phahonyothin Road, Klong Luang, Pathum Thani 12120, Thailand.
This study presents a new approach for fabricating 3D-printed self-healing hydrogels via light-assisted 3D printing, utilizing Schiff-base and covalent bonding formations resulting from the reaction between amine and aldehyde functional groups alongside the photopolymerization of methacrylate groups. Two distinct polymers, carboxymethyl chitosan (CMCs) and dextran, were first modified to yield methacrylate-modified carboxymethyl chitosan (CMCs-MA) and oxidized dextran (OD). The structural modifications of these polymers were confirmed using spectroscopic techniques, including H NMR and FTIR analyses.
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