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Doctors' satisfaction with the rehabilitation system for anti-terrorist operation participants: A factor analysis.
Heliyon
January 2025
Rutgers Global Health Institute, Rutgers School of Public Health, New Brunswick, NJ, USA.
Background: A war has a catastrophic effect on veterans' health. However, there is a knowledge gap about the veterans' rehabilitation system, requirements, and the satisfaction of doctor-organizers. The present study aims to assess the level of satisfaction of the doctor-organizers of health care with the existing rehabilitation system for anti-terrorist operation (ATO) veterans in Ukraine.
View Article and Find Full Text PDFHow to Put Survival After Cardiothoracic Interventions in the General Population Context: A Case-Based Practical Guideline to Calculate Cumulative Matched-General-Population Survival.
Circ Cardiovasc Qual Outcomes
January 2025
Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands. (X.W., M.L.N., K.M.V., P.G., J.R.G.E., A.J.J.C.B., J.J.M.T.).
Background: Observed patient survival after cardiothoracic interventions should ideally be placed in the context of matched-general-population survival. This study outlines several methodologies of matching general population mortality to the study sample, subsequently calculating cumulative matched-general-population survival, highlighting their respective advantages, disadvantages, and limitations.
Methods: A multicenter data set containing survival data after the Ross procedure was used for methodological illustration.
Sensor-combined organ-on-a-chip for pharmaceutical and medical sciences: from design and materials to typical biomedical applications.
Mater Horiz
January 2025
College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Organ-on-a-chip (OoC) is a breakthrough technology in biomedicine. As microphysiological systems constructed , OoCs can simulate the main structures and functions of human organs, thereby providing a powerful tool for drug screening and disease model construction. Furthermore, the coupling of OoCs and sensors has been an innovative discovery in the field of biomedical and electronic engineering in recent years.
View Article and Find Full Text PDFNext-generation pharmaceuticals: the rise of sildenafil citrate ODF for the treatment of men with erectile dysfunction.
Ther Deliv
January 2025
Global Specialty Excellence, Viatris Inc, New York, USA.
Orodispersible film (ODF) is one of the novel formulations that disintegrate rapidly in the mouth without the requisite for water compared to other conventional oral solid dosage formulations. This delivery system serves as a convenient mode of administration, especially in patients who have dysphagia and fluid restriction, being beneficial to pediatric, geriatric, and bedridden patients. A novel sildenafil ODF containing sildenafil citrate is formulated to be used in patients with erectile dysfunction (ED).
View Article and Find Full Text PDFPatient views on continued immune checkpoint inhibition following progression in advanced melanoma: A qualitative study.
Bull Cancer
January 2025
Palliative Care Unit, ULR 2694 METRICS, CHU de Lille, Université de Lille, 59000 Lille, France.
Introduction: Immune checkpoint inhibition has revolutionized the management of metastatic melanoma, including in the final stages of disease progression: because it is well tolerated, some teams do not discontinue it in hopes of slowing disease progression. The risks are that treatment may be continued unnecessarily, causing side effects, and reduce access to specialist palliative care, in addition to increasing the cost of treatment.
Method: We explored the experiences of 10 patients in a university hospital with metastatic melanoma under continued immune checkpoint inhibitors combined with specialist palliative care.
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