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Juvenile idiopathic arthritis: an update for the clinician. | LitMetric

Juvenile idiopathic arthritis: an update for the clinician.

Bull NYU Hosp Jt Dis

New York University School of Medicine, Division of Pediatric Rheumatology, New York, NY 10016, USA.

Published: May 2013

AI Article Synopsis

Article Abstract

Juvenile idiopathic arthritis (JIA) comprises a collection of all forms of chronic arthritis in childhood with no apparent cause. JIA is the most common rheumatic disease in children, and may result in significant pain, joint deformity, and growth impairment, with persistence of active arthritis into adulthood. Prior to the mid 1990s, the therapeutic armamentarium for JIA was more limited, utilizing non- specific agents, many with significant adverse effects. With the relatively recent use of biologics, one can provide more target-specific therapy, which may be better tolerated. Through continued translational research and clinical trials, one better understands the biology mediating disease, with the hope of offering safer, more effective medicine, and potential cure. This review will outline the clinical features of JIA, as well as provide the latest updates in current and future pharmacotherapy.

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