A platform for capture and release of circulating tumor cells is demonstrated by utilizing polymer grafted silicon nanowires. In this platform, integration of ligand-receptor recognition, nanostructure amplification, and thermal responsive polymers enables a highly efficient and selective capture of cancer cells. Subsequently, these captured cells are released upon a physical stimulation with outstanding cell viability.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786692PMC
http://dx.doi.org/10.1002/adma.201203185DOI Listing

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