Importance: Self-triage using web-based decision support could be a useful way to encourage appropriate care-seeking behavior and reduce health system surge in epidemics. However, the feasibility and safety of this strategy have not previously been evaluated.
Objective: To assess the usability and safety of Strategy for Off-site Rapid Triage (SORT) for Kids, a web-based decision support tool designed to translate clinical guidance developed by the Centers for Disease Control and Prevention to help parents and adult caregivers determine if a child with influenza-like illness requires immediate care in an emergency department (ED).
Design: Prospective pilot validation study conducted between February 8 and April 30, 2012. Staff who abstracted medical records and made follow-up calls were blinded to the SORT algorithm's assessment of the child's level of risk.
Setting: Two pediatric emergency departments in the National Capital Region.
Participants: Convenience sample of 294 parents and adult caregivers who were at least 18 years of age; able to read and speak English; and the parent or legal guardian of a child 18 years or younger presenting to 1 of 2 EDs with signs and symptoms meeting Centers for Disease Control and Prevention criteria for influenza-like illness.
Intervention: Completion of the SORT for Kids survey.
Main Outcome Measures: Caregiver ratings of the website's usability and the sensitivity of the underlying algorithm for identifying children who required immediate ED management of influenza-like illness, defined as receipt of 1 or more of 5 essential clinical services.
Results: Ninety percent of participants reported that the website was "very easy" to understand and use. Ratings did not differ by respondent race, ethnicity, or educational attainment. Of the 15 patients whose initial ED visit met explicit criteria for clinical necessity, the Centers for Disease Control and Prevention algorithm classified 14 as high risk, resulting in an overall sensitivity of 93.3% (exact 95% CI, 68.1%-99.8%). Specificity of the algorithm was poor.
Conclusions And Relevance: This pilot study suggests that web-based decision support to help parents and adult caregivers self-triage children with influenza-like illness is feasible. However, prospective refinement of the clinical algorithm is needed to improve its specificity without compromising patient safety.
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http://dx.doi.org/10.1001/jamapediatrics.2013.1573 | DOI Listing |
Diseases
December 2024
CSL Seqirus Inc., 25 Deforest Avenue, Summit, NJ 07901, USA.
Healthy working-age adults are susceptible to illness or caregiving requirements resulting from annual seasonal influenza, leading to considerable societal and economic impacts. The objective of this targeted narrative review is to understand the societal burden of influenza in terms of absenteeism and productivity loss, based on the current literature. This review includes 48 studies on the impact of influenza and influenza-like illness (ILI) and reports on the effect of influenza vaccination, age, disease severity, caring for others, comorbidities, and antiviral prophylaxis on absenteeism and productivity loss due to influenza/ILI, focusing on publications originating from Canada, Europe, and the United States.
View Article and Find Full Text PDFHum Vaccin Immunother
December 2025
Hangzhou Disease Prevention and Control Center, Hangzhou, P.R. China.
From 2020, influenza viruses circulation was largely affected by the global coronavirus disease (COVID-19) pandemic, notably leading to the extinction of the B/Yamagata lineage and raising questions about the relevance of the quadrivalent influenza vaccine, which includes this lineage. Evaluating vaccine effectiveness (VE) against influenza infections is important to inform future vaccine programs. A test-negative case-control study was conducted in five tertiary hospitals in Hangzhou, the capital city of Zhejiang province, China, enrolling medically-attended patients aged >6 months who presented with influenza-like illness (ILI) from October 1, 2023, to March 31, 2024.
View Article and Find Full Text PDFJ Pharm Health Care Sci
December 2024
Department of Clinical Pharmacy, School of Medicine, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, 200080, China.
Background: Oncolytic virus therapy is a rapidly evolving emerging approach for the medical management of cancer. Talimogene laherparepvec (T-VEC) is the first and only Food and Drug Administration (FDA)-approved oncolytic virus therapy. Considering that exactly how T-VEC works is not known, there is a strong need for a comprehensive pharmacovigilance study to identify safety signals of potential risks with T-VEC.
View Article and Find Full Text PDFPublic Health
December 2024
Agenzia Regionale Emergenza Urgenza Headquarters (AREU HQ), Milan, Italy.
Objectives: Influenza-like illness (ILI) refers to the set of symptoms associated with seasonal influenza infection. In Italy, the syndromic surveillance system RespiVirNet uses both epidemiological and virological data to monitor ILI incidence with a weekly cadence. To estimate ILI incidence in real time, several countries adopted surveillance systems which include data from the emergency-urgency (E-U) system.
View Article and Find Full Text PDFEcotoxicol Environ Saf
December 2024
Department of Epidemiology, School of Public Health, Southern Medical University (Guangdong Provincial Key Laboratory of Tropical Disease Research), No.1023-1063, Shatai South Road, Baiyun District, Guangzhou 510515, China. Electronic address:
Background: Although the link between fine particulate matter (PM) and influenza-like illness (ILI) is well established, the effect of the chemical constituents of PM on ILI remains unclear. This study aims to explore this effect in Guangzhou, China.
Methods: Daily data on ILI cases, PM levels, and specific PM constituents (black carbon [BC], chlorine [Cl], ammonia [NH], nitrate [NO], and sulfate [SO]) in Guangzhou, China, were collected for the period of 2014-2019.
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