Non-ablative bipolar and monopolar radiofrequency devices have been shown to be effective for the treatment of facial wrinkles. Recently, novel fractionated microneedle radiofrequency (FMRF) devices have been introduced. The aim of this study was to evaluate the clinical effectiveness and safety of FMRF for the treatment of periorbital wrinkles. Eleven women, aged 34-59 years, with periorbital wrinkles underwent three sessions of FMRF at 3-week intervals with a follow-up period of 3 months after treatment. Clinical improvement was evaluated using the Fitzpatrick Wrinkle Classification System (FWCS) and subjective satisfaction on a visual analog scale (VAS). The FWCS scores demonstrated significant improvement in periorbital wrinkles after treatment (P < 0.001). A satisfaction VAS score of more than 5, indicating high satisfaction, was obtained from 10 of 11 patients (91%) 3 months after treatment, and the mean satisfaction VAS score (n = 11) was 6.7. Patients undergoing treatment reported minimal pain, and neither long-lasting side-effects nor significant downtime was noted. This clinical study suggests that FMRF is a safe and tolerable method for successful treatment of periorbital wrinkles.
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http://dx.doi.org/10.1111/1346-8138.12046 | DOI Listing |
Int J Cosmet Sci
January 2025
Genomic Sciences and Biotechnology Program, Catholic University of Brasilia, Brasília, Federal District, Brazil.
Background: The aging of the skin, particularly around the periorbital region, is a complex process characterized by the accumulation of senescent cells, decreased collagen production, and reduced skin elasticity, leading to visible signs such as fine lines, wrinkles, and sagging.
Objective: This study investigates the efficacy of a novel topical formulation, OS-01 EYE, containing the senomorphic peptide, OS-01, along with other active ingredients, in improving the skin around the eyes.
Methods: A 12-week clinical study was conducted with 22 participants who applied OS-01 EYE twice daily.
Int Ophthalmol
December 2024
Department of Ophthalmology, Ankara Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Purpose: To investigate the efficacy of a comprehensive surgical approach for rejuvenation of the aging lower periorbita.
Methods: Between February 2018 and January 2023, 80 eyes of 40 patients with lower lid dermatochalasis (LLD), lower lid laxity (LLL) or orbicularis laxity of the lower lid (OL) admitted to the oculoplastic surgery department of our clinic were included in the study. 18 eyes had LLD, 14 eyes had LLL, 18 eyes had LLD and LLL, and 30 eyes had LLD, LLL and OL.
Clin Exp Dermatol
December 2024
Dinar State Hospital, Department of Dermatology, Afyonkarahisar, Turkey.
Background: Ionizing radiation (IR) is a occupational risk for healthcare professionals, which can result in a range of health issues.
Objectives: This study aims to assess the relationship between low-dose IR exposure and the development of early aging-related skin wrinkles in healthcare workers.
Methods: In the current cross-sectional study, 70 health workers exposed to low-dose ionizing radiation for at least five years were compared with 70 non-exposed health workers.
Introduction: Microneedling, a technique involving controlled dermal microwounding, and platelet-rich plasma (PRP) injections are both employed for skin rejuvenation. While both treatments individually show promise, limited research has explored their combined efficacy. This study aimed to evaluate the effectiveness of combining PRP injections with microneedling for aesthetic concerns around the eyes under standardized conditions.
View Article and Find Full Text PDFAnn Dermatol
December 2024
Department of Dermatology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.
Background: Botulinum toxin is commonly used for cosmetic enhancements in various applications. However, the pain experienced during the injection process remains a significant concern.
Objective: This study aimed to evaluate the effectiveness and safety of a needle-free microjet drug injector, powered by an Er:YAG laser, for the injection of botulinum toxin to treat crow's feet wrinkles.
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