An extract from the obituary for Sir Lawrence Bragg by M. F. Perutz [Nature (London), (1971), 233, 74-76] is given.
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A Nanosized {Ni } Cluster with a 'Flying Saucer' Topology Exhibiting Slow Relaxation of Magnetisation Phenomena at Both 15 K and 1.3 K.
Chemistry
January 2025
Department of Chemistry, Brock University, 1812 Sir Isaac Brock Way, L2S 3A1, St. Catharines, Ontario, Canada.
A high-nuclearity {Ni} complex (1) with a unique 'flying saucer' motif has been prepared from the organic chelate, α-methyl-2-pyridine-methanol (mpmH), in conjunction with bridging azido (N ) and peroxido (O ) ligands. Magnetic susceptibility measurements revealed the presence of both ferro- and antiferromagnetic exchange interactions between the metal centres in 1, and the stabilization of spin states with appreciable S values at two different temperature regimes. The end-on bridging azido and alkoxido groups are in all likelihood the ferromagnetic mediators, while the η:η:μ-bridging peroxides most likely promote the antiparallel alignment of the metals' spin vectors, yielding an overall non-zero spin ground state for the centrosymmetric compound 1.
View Article and Find Full Text PDFChanges to virus taxonomy and the ICTV Statutes ratified by the International Committee on Taxonomy of Viruses (2024).
Arch Virol
November 2024
The Biodesign Center for Fundamental and Applied Microbiomics, School of Life Sciences, Center for Evolution and Medicine, Arizona State University, Tempe, AZ, 85287-4701, USA.
Article Synopsis
- The article outlines recent updates to virus taxonomy approved by the International Committee on Taxonomy of Viruses (ICTV) in April 2024.
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Author Correction: CDK9 inhibition constrains multiple oncogenic transcriptional and epigenetic pathways in prostate cancer.
Br J Cancer
November 2024
Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia.
Innovative approaches in phenotypic beta-lactamase detection for personalised infection management.
Nat Commun
October 2024
The NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, Hammersmith Campus, London, United Kingdom.
Beta-lactamase-producing Enterobacteriaceae present a significant therapeutic challenge. Current developments in phenotypic diagnostics focus primarily on rapid minimum inhibitory concentration (MIC) determination. There is a requirement for rapid phenotypic diagnostics to improve antimicrobial susceptibility tests (AST) and aid prescribing decisions.
View Article and Find Full Text PDFOpioid use patterns following discharge from elective colorectal surgery: a prospective cohort study.
Surg Endosc
January 2025
Department of Surgery, McGill University, Montreal, QC, Canada.
Introduction: Opioid overprescription after colorectal surgery can lead to adverse events, persistent opioid use, and diversion of unused pills. This study aims to assess the extent to which opioids prescribed at discharge after elective colorectal surgery are consumed by patients.
Methods: This prospective cohort study included adult patients (≥ 18 yo) undergoing elective colorectal surgery at two academic hospitals in Montreal, Canada.
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