Successful treatment of vincristine induced ptosis and polyneuropathy with pyridoxine and pyridostigmine in a child with acute lymphoblastic leukemia.

Indian J Med Paediatr Oncol

Department of Pediatrics, Kasturba Medical Collge, Mangalore, Karnataka, India.

Published: July 2012

Vincristine is used in the treatment of solid tumors, lymphoma and leukemia in children. The dose-limiting toxicity is its neurotoxicity. We describe a 2-year-old girl with acute lymphoblastic leukemia who developed vincristine-induced polyneuropathy with bilateral ptosis and recovered on treatment with pyridoxine and pyridostigmine.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523480PMC
http://dx.doi.org/10.4103/0971-5851.103152DOI Listing

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