AI Article Synopsis
- The study presents a solid-state electrochemical method for quickly screening illegal adulterants in commercial phytotherapeutic products.
- It utilizes voltammetry of microparticles to differentiate between various families of drugs, including anorectics, anxiolytics, antidepressants, diuretics, and hypoglycemics.
- This technique involves recording unique voltammetric signals from solid micro- or nanosamples on graphite electrodes in aqueous solutions, providing a sensitive detection method.
Article Abstract
A solid state electrochemical method for screening different families of adulterant chemicals illegally added to commercial phytotherapuetic formulations is described. The proposed method, based on the voltammetry of microparticles approach, permits a fast and sensitive way to distinguish between anorexics (amfepramone, fenproporex, sibutramine), benzozodiazepinic anxiolytics (clonazepam, flurazepam, alprazolam, midazolam, medazepam, chlordiazepoxide, diazepam), antidepressants (bupropione, fluoxetine, sertraline, paroxetine), diuretics (hydrochlorothiazide, furosemide, chlortalidone, amiloride, spironolactone), and hypoglycemics (glimepiride, chlorpropamide, glibenclamide) based on characteristic voltammetric signals recorded on solid micro- or nanosamples attached to graphite electrodes immersed into aqueous electrolytes.
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| http://dx.doi.org/10.1016/j.jpba.2012.10.031 | DOI Listing |
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