Lymph nodes are compartmentalized organs but whether this feature has a role in T cell differentiation has been unclear. In this issue, Groom et al. (2012) reveal that spatially separated expression of two CXCR3 ligands guides Th1 cell development.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540980 | PMC |
| http://dx.doi.org/10.1016/j.immuni.2012.11.007 | DOI Listing |
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