Early clues of change in heart failure (HF) status, such as weight gain or reduced exercise tolerance, may be missed by caregivers in nursing homes (NHs) since daily weight measurement and functional assessments may not be performed routinely. These factors are likely to contribute to a delay in non-emergent care for the resident. The purpose of this study was to examine patterns of care activities provided in the NH setting to residents with HF and document variations in these care patterns across a random national sample of NHs. Care activities performed daily within a large proportion of NHs for residents with HF were assessment for changes in HF symptoms (94%), changes in mental status (91%), and changes in swelling/edema (85%). There was wide variation in care patterns. Not all evidence-based guidelines for HF care and monitoring were followed in the NH setting, which could affect hospitalizations and other outcomes.
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http://dx.doi.org/10.3928/19404921-20121204-02 | DOI Listing |
Klin Mikrobiol Infekc Lek
June 2023
Department of Clinical Microbiology, Pardubice Hospital, Czech Repubic, e-mail:
Objectives: The use of nonadherent dressings is part of care for chronic wounds. In this paper, we present the results of in vitro activity of several such dressings on bacteria most commonly found in chronic wounds.
Material And Methods: Selected bacterial strains were isolated from chronic wounds of patients in Pardubice Hospital in the period from February to May 2022.
Curr Opin Crit Care
January 2025
Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Purpose Of Review: This review aims to examine recent advances in the understanding of injury-induced endotheliopathy and therapeutics to mitigate its development in critically injured patients.
Recent Findings: Clinical studies have clearly demonstrated that syndecan-1 ectodomains can be found in circulation after various types of trauma and injury and correlates with worse outcomes. As the mechanisms of endotheliopathy are better understood, pathologic hyperadhesive forms of von Willebrand factor, along with a relative deficiency of its cleaving enzyme, a disintegrin and metalloprotease with thrombospondin type I motifs, member 13 (ADAMTS13), have emerged as additional biomarkers.
Appl Biochem Biotechnol
January 2025
Department of Internal Medicine-Cardiovascular, Guangzhou Twelfth People's Hospital, No.1, Tianqiang Road, Tianhe District, Guangzhou City, Guangdong Province, 510620, China.
Myocardial infarction (MI) is a coronary artery-related disease that seriously threatens human life and is the leading cause of sudden death worldwide, where a lack of nutrients and oxygen leads to an inflammatory response and death of cardiomyocytes. Ferroptosis is a form of non-apoptotic cell death associated with metabolic dysfunction, resulting in abnormal breakdown of glutamine and iron-dependent accumulation of reactive oxygen species (ROS) during metabolism. However, the molecular mechanism of ferroptosis in the pathogenesis of MI and the function of Klotho and KRAS on ferroptosis during MI remain unclear.
View Article and Find Full Text PDFAppl Biochem Biotechnol
January 2025
Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital Affiliated to Tianjin Medical University, No.154 Heping Road to Anshan, Tianjin City, 300052, People's Republic of China.
Dysregulated circular RNAs (circRNAs) has been revealed to be involved in pulmonary fibrosis progression. Herein, this study focused on exploring the function and mechanism of circRNA Zinc Finger MYM-Type Containing 2 (circZMYM2) on idiopathic pulmonary fibrosis (IPF) using transforming growth factor (TGF)-β1-stimulated fibroblasts. Human fibroblast cell lines IMR-90 and HFL1 were stimulated with TGF-β1 to mimic fibrosis condition in vitro.
View Article and Find Full Text PDFJ Med Syst
January 2025
Department of Computing, University of North Florida, 1 UNF Dr., Jacksonville, 32246, FL, USA.
The "no-show" problem in healthcare refers to the prevalent phenomenon where patients schedule appointments with healthcare providers but fail to attend them without prior cancellation or rescheduling. In addressing this issue, our study delves into a multivariate analysis over a five-year period involving 21,969 patients. Our study introduces a predictive model framework that offers a holistic approach to managing the no-show problem in healthcare, incorporating elements into the objective function that address not only the accurate prediction of no-shows but also the management of service capacity, overbooking, and idle resource allocation resulting from mispredictions.
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