AI Article Synopsis
Article Abstract
Understanding the mental states of others entails a number of cognitive processes known as Theory of Mind (ToM). A relationship between ToM deficits and executive disorders has been hypothesized in individuals with Parkinson's disease (PD). The present study was aimed at investigating the effect of dysexecutive deficits on ToM abilities in PD patients without dementia. Participants included 30 PD patients and 30 healthy subjects (HC). PD patients were divided into two groups according to their executive test performance: patients with poor (dysexecutive group; n=15) and normal (executively unimpaired group; n=15) performance. All participants were administered faux pas recognition written stories. The dysexecutive PD patients performed less accurately than both HC and executively unimpaired PD individuals on all faux pas story questions (p< 0.05); the executively unimpaired PD group performed as accurately as the HC group on the ToM tasks. Results of the study clearly demonstrate that PD is not tout court associated with ToM impairments and that these may occur in PD patients as a function of the degree of their executive impairment. Our findings also indirectly confirm previous data on the role of the prefrontal regions in mediating ToM capacities.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214465 | PMC |
| http://dx.doi.org/10.3233/BEN-129018 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mental fatigue increases perception of effort but does not compromise the inhibitory control of football referees during a match simulation physical task.
Eur J Sport Sci
January 2025
Graduate Program in Human Movement Sciences, Institute of Health Sciences, Federal University of Pará, Belem, Brazil.
Executive functioning (EF) in referees is associated with their decision-making during a match and can be affected by mental fatigue (MF), a psychobiological state induced by prolonged periods of cognitive activity or high cognitive demand within a short timeframe. Therefore, the aim of this study was to investigate the impact of MF on EF and the perception of effort during a physical task for football referees. Twelve male professional football referees were recruited (32 ± 7.
View Article and Find Full Text PDFF-PI-2620 Tau PET is associated with cognitive and motor impairment in Lewy body disease.
Brain Commun
December 2024
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94304, USA.
Co-pathology is frequent in Lewy body disease, which includes clinical diagnoses of both Parkinson's disease and dementia with Lewy bodies. Measuring concomitant pathology can improve clinical and research diagnoses and prediction of cognitive trajectories. Tau PET imaging may serve a dual role in Lewy body disease by measuring cortical tau aggregation as well as assessing dopaminergic loss attributed to binding to neuromelanin within substantia nigra.
View Article and Find Full Text PDFA multi-parametric MRI study on changes in the structure, function, and connectivity of thalamic subregions and their relationship with cognitive impairment in patients with subcortical ischemic vascular disease.
Brain Res
December 2024
Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address:
Introduction: Prior researches have reported abnormal changes of thalamus in patients with subcortical ischemic vascular disease (SIVD), which was usually analyzed as a whole. However, it was currently unclear whether the structure, function and connectivity of thalamic subregions were differentially affected by this disease and affected different cognitive functions.
Methods: This study recruited 30 SIVD patients with cognitive impairment (SIVD-CI), 30 SIVD patients with cognitive unimpaired (SIVD-CU) and 32 normal controls.
Data-driven CSF biomarker profiling: imaging and clinical outcomes in a cohort at risk of Alzheimer's disease.
Alzheimers Res Ther
December 2024
University of Pompeu Fabra (UPF), Barcelona, Spain.
Background: Cerebrospinal fluid (CSF) biomarkers of synaptic dysfunction, neuroinflammation, and glial response, complementing Alzheimer's disease (AD) core biomarkers, have improved the pathophysiological characterization of the disease. Here, we tested the hypothesis that the co-expression of multiple CSF biomarkers will help the identification of AD-like phenotypes when biomarker positivity thresholds are not met yet.
Methods: Two hundred and seventy cognitively unimpaired adults with family history (FH) of sporadic AD (mean age = 60.
The bidirectional relationship between subjective visual function and domain-specific cognition in cognitively unimpaired older adults and adults with mild cognitive impairment.
Front Aging Neurosci
November 2024
Interdisciplinary Neuroscience Program, University of Rhode Island, Kingston, RI, United States.
Article Synopsis
- Subjective visual impairment (VI) is linked to cognitive performance in both cognitively unimpaired (CU) older adults and patients with mild cognitive impairment (MCI) or Alzheimer's disease (AD).
- The study used the NEI-VFQ-25 and a neuropsychological test to explore this relationship, finding that CU adults had a positive link between subjective VI and visuospatial abilities.
- Results suggest that subjective VI complaints could serve as indicators for specific cognitive decline areas like attention, processing speed, and executive function in older individuals.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!