Two unprecedented phosphorus-containing iodinated polyacetylenes, phosphoiodyns A and B (1-2), were isolated from a Korean marine sponge Placospongia sp. Their structures were elucidated by spectroscopic data analysis. Phosphoiodyn A exhibited potent agonistic activity on human peroxisome proliferator-activated receptor delta (hPPARδ) with an EC(50) of 23.7 nM.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ol3031318 | DOI Listing |
Publication Analysis
Top Keywords
phosphorus-containing iodinated
8
iodinated polyacetylenes
8
sponge placospongia
8
phosphoiodyns unique
4
unique phosphorus-containing
4
polyacetylenes korean
4
korean sponge
4
placospongia unprecedented
4
unprecedented phosphorus-containing
4
polyacetylenes phosphoiodyns
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!