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Palladium-catalyzed trifluoromethylation of aromatic C-H bond directed by an acetamino group. | LitMetric

Palladium-catalyzed trifluoromethylation of aromatic C-H bond directed by an acetamino group.

Org Lett

Beijing National Laboratory of Molecular Sciences (BNLMS), College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.

Published: January 2013

The first palladium-catalyzed ortho-trifluoromethylation of the aromatic C-H bond directed by an acetamino group is reported. This method provides an efficient and green approach to synthesize the highly biological potential key structure of ortho-CF(3) acetanilides and anilines.

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Source
http://dx.doi.org/10.1021/ol302814xDOI Listing

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