Objective: To study the chemical constituents of Gentiana striata.
Methods: The constituents were isolated from the whole herb of Gentiana striata by recrystalization, silica gel column chromatography, polyamide column chromatography and Sephadex LH-20,etc. Their structures were elucidated through MS, 1H-NMR, 13C-NMR.
Results: -8 compounds were isolated and identified as: Desoxyloganin (1), Gmephiloside (2), 5,7,4'-trihydroxy-3'-methoxyflavone (3), (+)-8-hydroxypinoresinol (4) 3S,5R, 6R, 9S-tetra-hydroxymegastigmane (5), Quercetin-3-O-beta-D-glucoside (6), Ferulic acid (7) and Ursolic acid (8).
Conclusion: All the compounds are isolated for the first time from Gentiana striata.
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J Ethnopharmacol
February 2025
College of Life Science and Technology, Beijing University of Chemical Technology, 100029, Beijing, China. Electronic address:
Ethnopharmacological Relevance: Gentiana rigescens Franch. (G. rigescens), known as "Dian Long Dan" in Southern Yunnan Herbal, has a long history in traditional Chinese medicine for treating hepatitis, allergies, postherpetic neuralgia, cholecystitis and rheumatism.
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March 2024
Department of Burns And Plastic Surgery, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Mangiferin, a key bioactive constituent in Gentiana rhodantha, has a favorable impact on reducing blood sugar. A selective and sensitive UPLC MS/MS approach was developed for determining mangiferin in diabetic rats. Employing acetonitrile protein precipitation, chromatographic separation utilized a 2.
View Article and Find Full Text PDFHeliyon
April 2024
Key Laboratory for Tibet Plateau Phytochemistry of Qinghai Province, College of Pharmacy, Qinghai Nationalities University, Xining, 810007, China.
Herbal Maxim. (Family Gentianaceae), "Ma Hua Jiao" in Chinese, is a commonly used Chinese medicine. Secoiridoids and flavonoids have been identified as the major active components of herbal medicines used in the treatment of hepatitis, rheumatism and many other diseases.
View Article and Find Full Text PDFJ Ethnopharmacol
May 2024
Shanghai Inoherb Cosmetics Co.Ltd., Shanghai, 200080, China. Electronic address:
Ethnopharmacological Relevance: Gentiana species, known as the traditional Tibetan medicine "Bangjian," have been integral to clinical practice for millennia. Despite their longstanding use, our understanding of the variation in chemical constituents and bioactive effects among different species is limited.
Aim Of The Study: In the present study, we aimed to assess the differences in chemical profiles and bioactivities among four Gentiana species (G.
J Chromatogr Sci
November 2024
Department of Pharmaceutical Analysis, School of Pharmacy, Jilin Medical University, 5 Jilin Street, Fengman District, Jilin 132013, Jilin, China.
Radix gentianae (RG) is a traditional Chinese medicine used for the treatment of acute and chronic hepatitis in clinic. However, the chemical profile of RG is still unconfirmed, which hindered the progress of pharmacological study and clinical application. In this study, ultra-high performance liquid chromatography together with quadrupole time-of-flight mass spectrometry techniques were employed to separate and characterize the chemical constituents in RG.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!