[Effect of gold labeling immunoassay on field screening for Toxoplasma gondii infection of blood donors].

Objective: To evaluate the effect of gold labeling immunoassay (GLIA) on field screening for Toxoplasma gondii infection of blood donors.

Methods: A total of 1 056 specimens from the blood donors were examined by using GLIA and ELISA.

Results: The Toxoplasma IgG positive rates of GLIA and ELISA were 5.46% (49/898), and 4.90% (44/898), respectively, and there was no significant difference (chi2 = 0.610, P > 0.05). Those with positive results in both the two methods accounted for 4.45% (40/898), and those with negative results in both the two medhods accounted for 94.1% (845/898). The corresponding rate was 98.6% (885/898). Kappa index was 0.843, and the detection results of the two methods were consistent.

Conclusion: The detection efficiency of GLIA is proved to be of good agreement with ELISA, and GLIA has superior features, including easy implementation and quick efficiency, so it could be used for field screening for Toxoplasma gondii infection of blood donors.