Flavodonfuran: a new difuranylmethane derivative from the mangrove endophytic fungus Flavodon flavus PSU-MA201.

Nat Prod Res

a Department of Chemistry and Center of Excellence for Innovation in Chemistry , Faculty of Science, Prince of Songkla University, Hat Yai Songkhla 90112 , Thailand.

Published: June 2014

One new difuranylmethane derivative, flavodonfuran (1), together with tremulenolide A (2) was isolated from the mangrove-derived fungus Flavodon flavus PSU-MA201.The difuranylmethane derivative based on 1 is rare in natural products. Their structures were established by spectroscopic evidence. Compound 2 exhibited mild antibacterial and antifungal activities against Staphylococcus aureus ATCC25923 and Cryptococcus neoformans ATCC90113, respectively.

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http://dx.doi.org/10.1080/14786419.2012.750315DOI Listing

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