Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0376-8716(90)90140-a | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating the THBS2/PI3K/Akt pathway.
Sci Rep
January 2025
Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, People's Republic of China.
Epithelial‒mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells is believed to play a key role in the pathogenesis of proliferative vitreoretinopathy (PVR). The ability of Hirudo to promote blood flow and dispel blood stasis may be related to its anti-EMT effects. Through the use of a network pharmacology method, the mechanism by which Hirudo treats PVR was investigated in this study, and the findings were confirmed through in vitro cellular tests.
View Article and Find Full Text PDF"Chasing Rainbows" Beyond Kaposi Sarcoma's Dermoscopy: A Mini-Review.
Dermatopathology (Basel)
November 2024
Second Dermatology Department, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
The dermoscopic rainbow pattern (RP), also known as polychromatic pattern, is characterized by a multicolored appearance, resulting from the dispersion of polarized light as it penetrates various tissue components. Its separation into different wavelengths occurs according to the physics principles of scattering, absorption, and interference of light, creating the optical effect of RP. Even though the RP is regarded as a highly specific dermoscopic indicator of Kaposi's sarcoma, in the medical literature, it has also been documented as an atypical dermoscopic finding of other non-Kaposi skin entities.
View Article and Find Full Text PDFInterim safety and efficacy of gene therapy for RLBP1-associated retinal dystrophy: a phase 1/2 trial.
Nat Commun
September 2024
Department of Clinical Neuroscience, St. Erik Eye Hospital, Karolinska Institutet, Stockholm, Sweden.
Gene therapy holds promise for treatment of inherited retinal dystrophies, a group of rare genetic disorders characterized by severe loss of vision. Here, we report up to 3-year pre-specified interim safety and efficacy results of an open-label first-in-human dose-escalation phase 1/2 gene therapy clinical trial in 12 patients with retinal dystrophy caused by biallelic mutations in the retinaldehyde-binding protein 1 (RLBP1) gene of the visual cycle. The primary endpoints were systemic and ocular safety and recovery of dark adaptation.
View Article and Find Full Text PDF[Pricking-cupping combined with auricular thumbtack needle for postherpetic neuralgia of stagnation and blood stasis on chest and waist: a randomized controlled trial].
Zhongguo Zhen Jiu
August 2024
Department of Acupuncture and Moxibustion, Wuhan Hospital of Traditional Chinese and Western Medicine, Wuhan 430022, Hubei Province, China.
Objective: To observe the clinical effect of pricking-cupping combined with auricular thumbtack needle for postherpetic neuralgia (PHN) of stagnation and blood stasis on chest and waist.
Methods: A total of 98 patients with PHN of stagnation and blood stasis on chest and waist were randomized into an observation group (49 cases, 1 case was eliminated, 1 case dropped out) and a control group (49 cases, 1 case dropped out). In the observation group, treatment of pricking-cupping combined with auricular thumbtack needle was delivered, pricking and cupping were applied at Jiaji points (EX-B 2) at the related spinal segments corresponding to the pain sites and regional points, once every other day, auricular thumbtack needle was applied at Xin (CO), Shenmen (TF), Neifenmi (CO), Pizhixia (AT), etc.
[Research progress in chemical constituents and pigment extraction process of Carthami Flos].
Zhongguo Zhong Yao Za Zhi
April 2024
Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, Shaanxi University of Chinese Medicine Xi'an 712046, China International Joint Research Center on Resource Utilization and Quality Evaluation of Traditional Chinese Medicine of Hebei Province, Hebei University of Chinese Medicine Shijiazhuang 050200, China.
Article Synopsis
- Carthami Flos, derived from the safflower plant, is used in traditional Chinese medicine to improve blood circulation and relieve pain by activating blood flow and clearing blockages.
- It contains over 210 identified compounds, including pigments, flavonoids, and various organic compounds, with safflower yellow pigments being the most significant for medicinal use.
- Recent advancements have highlighted natural deep eutectic solvents as eco-friendly alternatives for extracting these pigments, providing insights for better utilization of Carthami Flos in medicinal applications.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!