Objective: To evaluate the accuracy of ultrasonography (US) and magnetic resonance imaging (MRI) in midline structures of fetal brain.
Methods: Thirty-two fetuses underwent US and MRI examinatiom. Imagings acquired from US and MRI were analysed, the results were compared with the final outcomes which were obtained after fetal birth or pathological study after induction of labor.
Results: There were 20 cases found abnormal in prenatal CNS ultrasonography (18 cases involving midline structures ). Among these 20 cases, 12 cases were normal in MRI and the fetuses were born in full-term without special problem, 8 cases were abnormal in MRI and fetal autopsy confirmed their abnormalities. Diagnostic accuracy rate of US was 93.8%, sensitivity was 100%, specificity was 87.5%, positive predictive value was 88.9%, negatvie predictive value was 100%. Diagnostic accuracy rate of MRI was 100%, modifying the US results in 4 cases.
Conclusion: US and MRI examinations are important in fetal central nervous system. US could be the first line examination, and MRI is an important supplement because of the high diagnostic accuracy, especially in the image study of midline structures of fetal brain.
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J Vasc Access
December 2024
Clinical Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
The fibroblastic sleeve is a structure potentially enveloping any intravascular device. At ultrasound scan, it typically presents as a thin layer of variably echogenic material covering the catheter surface, which usually tends to remain into the vessel after the catheter removal. However, several case reports have documented its migration toward the heart or pulmonary artery after a central venous catheter removal.
View Article and Find Full Text PDFAnn Anat
December 2024
Department of Urology, Graduate School of Medicine and Dentistry, Hiroshima University School of Medicine, Hiroshima, Japan.
Background: There is little information about when and how cavernosal sinusoidal endothelia develop in the external genitalia of fetuses.
Methods: We examined histological sections of erectile tissue in 37 human fetuses (25 males and 12 females) whose gestational age (GA) ranged from 8 to 40 weeks.
Results: The sinusoidal lumen was filled with blood in the glans of the penis and clitoris at a GA of 10 to 11 weeks, and in the corpus spongiosum at a GA of 15 to 16 weeks.
Brain Commun
December 2024
Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona 08005, Spain.
CSF concentrations of β-amyloid 42 (Aβ42) and phosphorylated tau (p-tau) are well-established biomarkers of Alzheimer's disease and have been studied in relation to several neuropathological features both in patients and in cognitively unimpaired individuals. The CSF p-tau/Aβ42 ratio, a biomarker combining information from both pathophysiological processes, has emerged as a promising tool for monitoring disease progression, even at pre-clinical stages. Here, we studied the association between the CSF p-tau/Aβ42 ratio with downstream markers of pre-clinical Alzheimer's disease progression including brain structure, glucose metabolism, fibrillary Aβ deposition and cognitive performance in 234 cognitively unimpaired individuals, who underwent cognitive testing, a lumbar puncture, MRI, 18F-fluorodeoxyglucose and 18F-flutemetamol PET scanning.
View Article and Find Full Text PDFJ Med Case Rep
December 2024
Department of Neurosurgery, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Background: Giant prolactinoma (size > 4 cm) is a rare condition and accounts for less than 1% of pituitary adenomas. In even rarer cases, these lesions may involve craniocervical structures requiring surgical intervention. The present case is the largest reported giant prolactinoma (99 × 72 × 57 mm).
View Article and Find Full Text PDFJBJS Case Connect
October 2024
Twin Cities Spine Center, Minneapolis, MN.
Case: A patient presented with midline back pain radiating into the left lower extremity. Magnetic Resonance images revealed an abnormal midline dorsal structure described as a facet cyst. Rupture was attempted by spinal needle under fluoroscopic guidance.
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