Growing evidence links perceptions of neighborhood disorder to adverse health outcomes but little is known about psychological processes that may mediate this association. We tested the hypothesis that two psychological mechanisms-agonistic striving and subordination-mediate the link between perceived neighborhood disorder and hypertension risk in youth. Perceived neighborhood disorder, agonistic striving, subordination experiences, negative affect, obesity, and ambulatory blood pressure during daily activities (48 h) were assessed in a multiethnic sample of 167 low- to middle-income urban adolescents. Path analyses revealed that agonistic striving, subordination, and obesity each independently mediated the association between neighborhood disorder and blood pressure; these variables accounted for 73 % of the shared variance, 42 % of which was explained by agonistic striving. The direct relationship between perceived neighborhood disorder and blood pressure was no longer significant in the presence of these mediators. Negative affect was associated with neighborhood disorder and subordination, but not blood pressure. Agonistic striving proved to be a significant and substantial mediator of the association between perceived neighborhood disorder, blood pressure, and future hypertension risk. New research should seek to clarify the processes by which stressful neighborhoods induce persistent agonistic motives and perceptions of subordination in adolescents.
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http://dx.doi.org/10.1007/s10865-012-9467-4 | DOI Listing |
ACS Chem Neurosci
January 2025
Laboratory for Innovative Drugs (Lab4IND), Computational Drug Design Center (HITMER), Bahçeşehir University, 34734 İstanbul, Türkiye.
is implicated in a range of conditions, including autism spectrum disorder, intellectual disability, seizures, autosomal recessive nonsyndromic intellectual disability, heterotaxy, and ciliary dysfunction. In order to understand the molecular mechanisms underlying these conditions, we focused on the structural and dynamic activity consequences of mutations within this gene. In this study, whole exome sequencing identified the c.
View Article and Find Full Text PDFAnn Thorac Surg Short Rep
December 2024
Division of Cardiology, Department of Pediatrics, Children's National Hospital, Washington, DC.
Background: Disadvantaged socioeconomic status correlates with adverse outcomes for patients with congenital heart disease. We examined individual and neighborhood characteristics associated with adverse short-term surgical outcomes and investigated potential drivers of disparities.
Methods: Single-center retrospective analysis collected clinical and demographic information on cardiovascular surgery patients over a 15-year period (2007-2022) from the District of Columbia metropolitan area.
Sleep Health
January 2025
University of Texas at San Antonio, Department of Sociology and Demography, San Antonio, Texas, United States.
Objectives: Drawing on the socioecological model of sleep health, we formally examine the association between neighborhood disorder and sleep efficiency. While most studies focus on direct associations with neighborhood context, we also consider whether the relationship between religious attendance and sleep efficiency varies as a function of neighborhood disorder.
Design: We use ordinary least squares regression to model cross-sectional survey data.
BMJ Open
January 2025
Cardiologie, Trousseau Hospital, Chambray-les-Tours, France.
Introduction: Several cardiovascular outcome trials have been conducted to assess the cardiovascular safety and efficacy of glucagon-like peptide-1 receptor agonists (GLP1-RAs) on cardiorenal outcomes in patients with type-2 diabetes (T2D). However, the strict requirements of randomised controlled trials to avoid most confounding factors are at the expense of external validity. Using national real-world data, we aimed to evaluate the effectiveness of GLP-1RAs in association with metformin especially on cardiovascular events, hospitalisation for heart failure and all-cause death in comparison with other diabetes treatment schemes using dipeptidyl peptidase IV inhibitors, sulfonylureas/glinides or insulin also associated with metformin.
View Article and Find Full Text PDFJ Cardiopulm Rehabil Prev
January 2025
Author Affiliations: Faculty of Health, Dalhousie University, Halifax, Nova Scotia, Canada (Ms Langley); Bluewater Health, Sarnia, Ontario, Canada and School of Kinesiology (Exercise and Health Psychology Lab), Western University, London, Ontario, Canada (Dr Campbell); Physical Activity and Chronic Disease Prevention Unit, University of British Columbia, Vancouver, British Columbia, Canada(Dr Warburton); School of Exercise Science, Physical and Health Education, Faculty of Health, University of Victoria, Victoria, British Columbia, Canada (Dr Rhodes); Department of Kinesiology & Physical Education, McGill University, Montreal, Quebec, Canada (Dr Sweet); Department of Medicine, Division of Cardiology, Dalhousie University, Halifax, Nova Scotia, Canada (Dr Giacomantonio); School of Health and Human Performance and the Healthy Populations Institute, Dalhousie University, Halifax, Nova Scotia, Canada (Dr Rainham); Faculty of Kinesiology & Recreation Management, University of Manitoba, Winnipeg, Manitoba, Canada (Dr Strachan); Department of Applied Human Sciences, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada (Dr Saunders); and Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada (Dr Blanchard).
Purpose: Little research has focused on the potential impact that the environment plays in shaping cardiac rehabilitation (CR) patient sedentary time (ST) and physical activity (PA). To address this, the current study generated daily path areas (DPAs) based on the locations they visited during and after they completed CR.
Methods: Patients in CR (n = 66) completed a survey and wore an accelerometer and Global Positioning System receiver for 7 days early (first month), late (last 2 weeks of program), and 3 months after completing CR.
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