The nature of stem and progenitor cells in the mammary epithelium, and the relevance of cleared fat pad transplantation as a functional assay for them, has been thrown into doubt by recent lineage-tracking studies. Now two new studies based on tracking the progeny of Wnt-responsive cells are starting to help make sense of this fascinating problem.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053131 | PMC |
http://dx.doi.org/10.1186/bcr3351 | DOI Listing |
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