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A Comparative Study of One-Stage Pre-pectoral Implant Breast Reconstruction With and Without Mesh.
Cureus
December 2024
Surgery, The Royal Wolverhampton NHS Trust, Wolverhampton, GBR.
Background Pre-pectoral implant-based breast reconstruction has become increasingly popular because it is associated with less postoperative pain and earlier recovery than traditional sub-pectoral techniques. Acellular dermal matrix (ADM) in pre-pectoral reconstruction is thought to provide additional support for the implant and improve cosmetic outcomes. However, it leads to additional costs.
View Article and Find Full Text PDFNon-alcoholic fatty liver disease (NAFLD) is a chronic condition characterized by hepatic steatosis in the absence of significant alcohol consumption and is increasingly recognized as the hepatic manifestation of metabolic syndrome (MetS). This review aims to explore the molecular mechanisms underlying the interaction between NAFLD, insulin resistance (IR), and MetS, with a focus on identifying therapeutic targets. A comprehensive review of existing literature on NAFLD, IR, and MetS was conducted.
View Article and Find Full Text PDFExploration of interprofessional collaboration for the diagnosis of infections and antibiotic prescription in nursing homes using multiple case study observational research.
JAC Antimicrob Resist
February 2025
Inserm, INSPIIRE, Université de Lorraine, Nancy F-54000, France.
Background: Antibiotic resistance in nursing homes (NHs) is inconsistently tackled by antimicrobial stewardship programmes. The literature on individual determinants of antibiotic prescriptions (APs) in NHs is extensive. However, less is known about the structural determinants of AP in NHs.
View Article and Find Full Text PDFMethods for extrapolating costs and effects in economic evaluations of telehealth interventions: a scoping review protocol.
BMJ Open
December 2024
Department of Health Science and Technology, Faculty of Health, Aalborg University, Aalborg, Denmark.
Introduction: Reviews of economic evaluations of telehealth interventions found that the current evidence is inconsistent with standard guidelines for conducting economic evaluation. The reviews conclude that most economic evaluations of telehealth interventions are small-scale and short-term. The choice of time horizon in economic evaluation, in general, is an important part.
View Article and Find Full Text PDFCost-effectiveness of metacognitive therapy for cardiac rehabilitation participants with symptoms of anxiety and/or depression: analysis of a randomised controlled trial.
BMJ Open
December 2024
Greater Manchester Mental Health NHS Foundation Trust, Manchester, UK.
Objectives: The burden of cardiovascular disease (CVD) is increasing. Cardiac rehabilitation (CR) is a complex intervention offered to patients with CVD, following a heart event, diagnosis or intervention, and it aims to reduce mortality and morbidity. The objective of this within-trial economic evaluation was to compare the cost-effectiveness of metacognitive therapy (MCT) plus usual care (UC) to UC, from a health and social care perspective in the UK.
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