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The amyloidoses: clinical features, diagnosis and treatment. | LitMetric

The amyloidoses: clinical features, diagnosis and treatment.

Methodist Debakey Cardiovasc J

Baylor College of Medicine, Houston, TX, USA.

Published: May 2013

AI Article Synopsis

  • Amyloidosis is a rare condition characterized by the accumulation of insoluble amyloid proteins in organs, leading to potential organ failure and mortality.
  • It impacts fewer than 200,000 individuals in the U.S., classifying it as a rare disease per the National Institutes of Health.
  • Identifying the specific type of amyloid protein involved is crucial for prognosis and treatment, as approaches differ based on the underlying cause.

Article Abstract

Amyloidosis is a rare disorder in which insoluble amyloid proteins are deposited in body organs, causing abnormal protein build-up in tissues and eventually leading to organ dysfunction and death. It affects less than 200,000 people in the United States, classifying it as a rare disease according to the National Institutes of Health. Definitive determination of the underlying protein is critical since prognosis and treatment of amyloidosis can vary widely depending on the responsible protein. The following paper describes the various types and clinical features of amyloidosis and provides an overview of current diagnostic tools and therapies.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487569PMC
http://dx.doi.org/10.14797/mdcj-8-3-3DOI Listing

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