Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513778PMC
http://dx.doi.org/10.1007/s12310-012-9087-8DOI Listing

Publication Analysis

Top Keywords

advances challenges
4
challenges school-based
4
school-based intervention
4
intervention anxious
4
anxious depressed
4
depressed youth
4
youth identifying
4
identifying addressing
4
addressing issues
4
issues sustainability
4

Similar Publications

Ocular surface chemical injuries often result in permanent visual impairment and necessitate complex, long-term treatments. Immediate and extensive irrigation serves as the first-line intervention, followed by various therapeutic protocols applied throughout different stages of the condition. To optimize outcomes, conventional regimens increasingly incorporate biological agents and surgical techniques.

View Article and Find Full Text PDF

β-secretase (BACE1) is instrumental in amyloid-β (Aβ) production, with overexpression noted in Alzheimer's disease (AD) neuropathology. The interaction of Aβ with the receptor for advanced glycation endproducts (RAGE) facilitates cerebral uptake of Aβ and exacerbates its neurotoxicity and neuroinflammation, further augmenting BACE1 expression. Given the limitations of previous BACE1 inhibition efforts, the study explores reducing BACE1 expression to mitigate AD pathology.

View Article and Find Full Text PDF

Tendon injuries present significant medical, social, and economic challenges globally. Despite advancements in tendon injury repair techniques, outcomes remain suboptimal due to inferior tissue quality and functionality. Tissue engineering offers a promising avenue for tendon regeneration, with biocompatible scaffolds playing a crucial role.

View Article and Find Full Text PDF

Circular RNAs in cancer: roles, mechanisms, and therapeutic potential across colorectal, gastric, liver, and lung carcinomas.

Discov Oncol

January 2025

Department of Bioscience and Biotechnology, Banasthali Vidyapith, Niwai-Tonk, Rajasthan, 304022, India.

The prominence of circular RNAs (circRNAs) has surged in cancer research due to their distinctive properties and impact on cancer development. This review delves into the role of circRNAs in four key cancer types: colorectal cancer (CRC), gastric cancer (GC), liver cancer (HCC), and lung cancer (LUAD). The focus lies on their potential as cancer biomarkers and drug targets.

View Article and Find Full Text PDF

Estimating spatiotemporal maps of greenhouse gases (GHGs) is important for understanding climate change and developing mitigation strategies. However, current methods face challenges, including the coarse resolution of numerical models, and gaps in satellite data, making it essential to improve the spatiotemporal estimation of GHGs. This study aims to develop an advanced technique to produce high-fidelity (1 km) maps of CO and CH over the Arabian Peninsula, a highly vulnerable region to climate change.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!