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Second Complete Remission of Relapsed Stage IV Non-Small Cell Lung Cancer Following Retreatment. | LitMetric

Second Complete Remission of Relapsed Stage IV Non-Small Cell Lung Cancer Following Retreatment.

Tuberc Respir Dis (Seoul)

Department of Internal Medicine, Chungnam National University Hospital & Cancer Research Institute, Chungnam National University School of Medicine, Daejeon, Korea.

Published: April 2012

AI Article Synopsis

  • Non-small cell lung cancer (NSCLC) is the most common cause of cancer deaths, often diagnosed at an advanced stage.
  • Complete remission (CR) is difficult to achieve solely with traditional chemotherapy or targeted therapies.
  • Two patients with advanced NSCLC who initially achieved CR with chemotherapy experienced a recurrence, but after retreatment with the same regimens, they again reached CR and have maintained this status.

Article Abstract

Non-small cell lung cancer (NSCLC) is the leading cause of cancer related deaths. Most patients were presented with advanced disease at the time of diagnosis. In advanced NSCLC, it is almost impossible to anticipate complete remission by using only cytotoxic chemotherapy or molecularly targeted agents. In our case, two patients were diagnosed as advanced NSCLC and received chemotherapy. They achieved complete response (CR). After finishing treatment, disease recurred. They were retreated with the same regimens and achieved second CR. Until now, they have received each regimen, continuously, and the CR state has been maintained.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510290PMC
http://dx.doi.org/10.4046/trd.2012.72.4.381DOI Listing

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