Objective: To estimate the prevalence of DR and to correlate cardiometabolic, sociodemographic, and oxidant/antioxidant imbalance data to the prevalence of DR.
Design: This case-control study included type 2 DM (T2 DM) patients with DR (n = 66), T2 DM patients without DR (N = 84), and healthy controls (n = 45) without DR, in Kinshasa town. Diet, albuminemia, serum vitamins, and 8-isoprostane were examined.
Results: No intake of safou (OR = 2.7 95% CI 1.2-5.8; P = 0.014), low serum albumin <4.5 g/dL (OR-2.9 95% CI 1.4-5.9; P = 0.003), no intake of fumbwa (OR = 2.8 95% CI 1.2-6.5; P = 0.014), high 8-isoprostane (OR = 14.3 95% CI 4.5-46; P<0.0001), DM duration ≥ 5 years (OR = 3.8 95% CI 1.6-9.1; P = 0.003), and low serum vitamin C (OR = 4.5 95% CI 1.3-15.5; P = 0.016) were identified as the significant independent determinants of DR.
Conclusion: The important role of oxidant/antioxidant status imbalance and diet is demonstrated in DR.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513305 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049411 | PLOS |
Publication Analysis
Top Keywords
Similar Publications
Dietary intake, forest foods, and anemia in Southwest Cameroon.
PLoS One
February 2020
Department of Nutrition and Food Science, University of Ghana, Accra, Ghana.
Background: Forest cover has been associated with higher dietary diversity and better diet quality in Africa. Anemia prevalence among women of reproductive age in sub-Saharan Africa is very high and diet is one known contributor of a high prevalence rate. We investigated whether living in communities with high forest cover was associated with better diet quality and lower anemia prevalence among women of reproductive age in Southwest Cameroon.
View Article and Find Full Text PDFMelinjo (Gnetum gnemon L.) seed extract induces uncoupling protein 1 expression in brown fat and protects mice against diet-induced obesity, inflammation, and insulin resistance.
Nutr Res
October 2018
Laboratory of Biochemistry, Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan; School of Biological Sciences, Tokai University, Sapporo, Hokkaido 005-8601, Japan. Electronic address:
Dietary supplementation with melinjo (Gnetum gnemon L.) seed extract (MSE) has been proposed as an anti-obesity strategy. However, it remains unclear how MSE modulates energy balance.
View Article and Find Full Text PDFMelinjo (Gnetum gnemon) Seed Extract Consumption during Lactation Improved Vasodilation and Attenuated the Development of Hypertension in Female Offspring of Fructose-Fed Pregnant Rats.
Birth Defects Res
January 2018
Course of Environmental Adaptation Science, Graduate School of Environmental Science, Hokkaido University, Sapporo, Japan.
Background: Fructose intake has been correlated with increased prevalence of metabolic disorders including hypertension. In pregnant rats, fructose intake has been reported to have adverse effects on the health of its offspring. This study investigated the effects of gestational maternal fructose consumption and if supplementation with melinjo seed extracts to the maternal diet during lactation could benefit the offspring in later life.
View Article and Find Full Text PDFRecipe standardization, nutrient composition and sensory evaluation of waterleaf (Talinum triangulare) and wild spinach (Gnetum africanum) soup "afang" commonly consumed in South-south Nigeria.
Food Chem
January 2018
Department of Biochemistry (Human Nutrition and Dietetics Unit), Faculty of Basic Medical Sciences, University of Calabar, Calabar, Cross River State, Nigeria. Electronic address:
One hundred recipes of waterleaf and wild spinach soup (afang) consumed among the Ibibios in South-south Nigeria were collected through interview and questionnaire from indigenous homemakers and food sellers, harmonized, standardized, prepared and their nutrient content calculated. Mean weights of ingredients were calculated to obtain the control recipe. Major ingredients in the soup were analyzed chemically.
View Article and Find Full Text PDFMelinjo (Gnetum gnemon) extract intake during lactation stimulates hepatic AMP-activated protein kinase in offspring of excessive fructose-fed pregnant rats.
Reprod Biol
June 2016
Department of Nutrition, Faculty of Health Sciences, Aomori University of Health and Welfare, Aomori 030-8505, Japan. Electronic address:
Excessive maternal fructose intake during pregnancy and in early postnatal life has metabolic consequences for the offspring. We investigated the effects of melinjo (Gnetum gnemon) extract (MeE) intake during lactation on the expression and phosphorylation of adenosine monophosphate-activated protein kinase (AMPK) in the liver of offspring from excessive fructose-fed pregnant dams. Pregnant Wistar rats received a normal diet and 100g/L fructose solution during gestation ad libitum.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!