Background: There is no consensus in postoperative rehabilitation regimen for people who had undergone surgery for degenerative medial meniscus damage. The aim of this study was to examine whether it is beneficial to undergo postoperative physiotherapy after surgery for these patients.
Methods: A prospective randomized controlled clinical trial. Over a 4 month period, 70 participants were randomly assigned into a high repetitive, high dosage medical exercise therapy group (EG) (n = 36) or into a control group (CG) (n = 34). Pain was a composite score of visual analogue scale (VAS). Function was measured with a functional assessment questionnaire (KOOS). Muscle strength was measured with a five repetition maximum test of quadriceps femoris.
Results: Prognostic variables were similar between the groups at baseline. Five (7%) people dropped out during the treatment period. The EG achieved significantly better outcome effects than the CG at pain (VAS reduced 1.9 in EG and 0.6 in CG) and function (KOOS decreased 18 in EG and only 6 in CG).
Conclusions: For people who have undergone surgery for degenerative meniscus damage, postoperative high repetitive, high dosage medical exercise therapy is an efficient treatment alternative compared to no rehabilitation.
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http://dx.doi.org/10.4021/jocmr1100w | DOI Listing |
BMC Geriatr
December 2024
ZHAW Zurich University of Applied Sciences, Winterthur Institute of Health Economics, Winterthur, Switzerland.
Background: Fall prevention programmes are essential interventions in societies with aging populations. This study assessed the fall rate and other health outcomes, as well as the cost-effectiveness of a home-based fall prevention programme for community-dwelling older people. In a single home visit, trained physical or occupational therapists performed fall risk assessments, eliminated environmental risk factors, and provided tailored exercises.
View Article and Find Full Text PDFBMC Health Serv Res
December 2024
National Commission on Certification of Physician Assistants, 12000 Findley Road, Suite 200, Johns Creek, Georgia, 30097, USA.
Background: Physician assistants/associates (PAs), due to their broad medical education and certification, have the flexibility to change specialties throughout their careers. Prior studies suggest that between half and three-quarters exercise this option at some point in their career, and a third do so within the first decade. However, more research is needed to understand the factors associated with PAs changing vs.
View Article and Find Full Text PDFCell Signal
December 2024
Department of Rehabilitation, School of Medical Technology, Tianjin Medical University, Tianjin 300070, China. Electronic address:
This study aimed to investigate the underlying mechanisms by which physical exercise mitigates muscle atrophy induced by Dexamethasone (Dex). A muscle atrophy model was established in the mouse C2C12 cell line and 8-week-old mice treated with Dex, with subsequent verification of phenotype and atrogene expression. The potential benefits of combined aerobic and resistance exercise in mitigating muscle atrophy were then examined.
View Article and Find Full Text PDFJ Proteomics
December 2024
School of Biological Sciences, University of Canterbury, Christchurch 8041, New Zealand; Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Australia; Department of Medicine, University of Otago, Christchurch 8014, New Zealand; Biomolecular Interaction Centre, School of Biological Sciences, University of Canterbury, Christchurch 8140, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1010, New Zealand. Electronic address:
Extreme heterogeneity exists in the hypersensitive stress response exhibited by the dystrophin-deficient mdx mouse model of Duchenne muscular dystrophy. Because stress hypersensitivity can impact dystrophic phenotypes, this research aimed to understand the peripheral pathways driving this inter-individual variability. Male and female mdx mice were phenotypically stratified into "stress-resistant" or "stress-sensitive" groups based on their response to two laboratory stressors.
View Article and Find Full Text PDFEBioMedicine
December 2024
Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Section for Clinical Immunology and Infectious Diseases, Oslo University Hospital Rikshospitalet, Oslo, Norway. Electronic address:
Background: The Bari-SolidAct randomized controlled trial compared baricitinib with placebo in patients with severe COVID-19. A post hoc analysis revealed a higher incidence of serious adverse events (SAEs) among SARS-CoV-2-vaccinated participants who had received baricitinib. This sub-study aimed to investigate whether vaccination influences the safety profile of baricitinib in patients with severe COVID-19.
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