Objectives: The study explored the presence of stress symptoms among orthotopic liver transplantation (OLT) recipients and investigated how stress symptoms are linked to health-related quality of life (HRQOL). A new concept of adjustment disorder as a stress response syndrome according to Maercker was considered.
Methods: We recruited 76 OLT recipients, all of whom had been treated in the Department of Surgery, Division of Transplantation Surgery, University of Medicine of Graz, Austria. A self-rating scale was administered to evaluate stress symptoms (PTSS-10). The data on health-related quality of life were obtained from the SF-36 (Health Status Questionnaire).
Results: Following OLT 30.3 % (n = 23) of the sample suffered from stress symptoms. In the group of patients suffering from stress symptoms there were significant impairments in health related quality of life in the SF-36 health-related domains physical functioning, role physical, pain, general health, vitality, social functioning, role emotional, and mental health.
Conclusions: OLT recipients may face a major risk of OLT-related postoperative stress symptoms in the sense of adjustment disorders according to Maercker. Stress symptoms are highly associated with impairments in quality of life.
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http://dx.doi.org/10.13109/zptm.2012.58.4.417 | DOI Listing |
Eur J Med Res
January 2025
Department of Rehabilitation Medicine, The Affiliated Hospital of Yunnan University, No. 176 Qingnian Road, Wuhua District, Kunming, Yunnan, China.
Background: Stress hyperglycemia ratio (SHR) has been linked to prognosis of cerebrovascular diseases. Nevertheless, the association between SHR and severe disturbance of consciousness (DC) and mortality among patients with cerebral infarction remains explored. This study seeks to assess the predictive potential of SHR for severe DC and mortality among patients with cerebral infarction.
View Article and Find Full Text PDFAIDS Behav
January 2025
Division of Infectious Diseases, Amsterdam University Medical Center, University of Amsterdam, G7, Meibergdreef 9, Amsterdam, 1105 AZ, The Netherlands.
People with HIV (PWH) are at greater risk of experiencing mental health problems, such as depression and post-traumatic stress disorder (PTSD). The purpose of our study was to determine the prevalence of posttraumatic stress disorder PTSD in PWH. PWH in care Amsterdam University Medical center (Amsterdam UMC) with access to the electronic patient portal were offered patient-reported outcome measures (PROMs) between May 2022 and May 2023, including the PC-PTSD-5 screen for PTSD as part of routine clinical care.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Nutrition, School of Public Health, Zabol University of Medical Sciences, Bagheri St., Shahid Rajaei St., Zabol, 9861615881, Iran.
Knee osteoarthritis (KOA) is a prevalent chronic condition characterized by inflammation and oxidative stress, particularly in individuals over 40. Dietary factors, specifically dietary acid load (DAL), may influence these pathological processes. However, the relationship between DAL and inflammatory markers, oxidative stress, and clinical features in patients with KOA remains unexplored.
View Article and Find Full Text PDFBiochemistry (Mosc)
December 2024
Moscow Institute of Physics and Technology, Dolgoprudny, 141701, Russia.
Activation of the p38 mitogen-activated protein kinase (MAPK) pathways is vital in regulating cell growth, differentiation, apoptosis, and stress response, significantly affecting tumorigenesis and cancer progression. We developed a bioinformatic technique to construct an interactome network-based molecular pathways for genes of interest and quantify their activation levels using high-throughput gene expression data. This study is focused on the p38α, p38β, p38γ, and p38δ kinases, examining their activation levels (PALs) based on transcriptomic data and their associations with survival and drug responsiveness across various cancer types.
View Article and Find Full Text PDFCardiovasc Revasc Med
January 2025
Weatherhead PET Imaging Center, Division of Cardiology, Department of Medicine, McGovern Medical School at UTHealth and Memorial Hermann Hospital, Houston, TX, United States of America.
Patients with angina but without obstructive epicardial coronary disease still require a specific mechanistic diagnosis to enable targeted treatment. The overarching term "coronary microvascular dysfunction" (CMD) has been applied broadly - but is it correct? We present a series of case examples culminating a systematic exploration of our large clinical database to distinguish among four categories of coronary pathophysiology. First, by far the largest group of "no stenosis angina" patients exhibits subendocardial ischemia during intact flow through diffuse epicardial disease during dipyridamole vasodilator stress.
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