Vaginal toxic shock reaction triggering desquamative inflammatory vaginitis.

J Low Genit Tract Dis

Departments of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, PA 19102, USA.

Published: January 2013

Objective: The study aimed to report 2 cases of desquamative inflammatory vaginitis associated with toxic shock syndrome toxin 1 (TSST-1)-producing Staphylococcus aureus strains.

Materials And Methods: Case report of 2 patients, 1 with an acute and 1 with a chronic presentation, diagnosed with desquamative inflammatory vaginitis on the basis of clinical findings and wet mount microscopy. Pretreatment and posttreatment vaginal bacterial and yeast cultures were obtained.

Results: Pretreatment vaginal bacterial cultures from both patients grew TSST-1-producing S. aureus. Subsequent vaginal bacterial culture results after oral antibiotic therapy were negative.

Conclusions: Desquamative inflammatory vaginitis may be triggered through TSST-1-mediated vaginal toxic shock reaction.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522853PMC
http://dx.doi.org/10.1097/LGT.0b013e3182656991DOI Listing

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