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| http://dx.doi.org/10.1016/j.mayocp.2012.08.018 | DOI Listing |
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Pellagra: An Unusual Cause for Altered Mental Status.
Cureus
October 2024
Medicine, Johns Hopkins University School of Medicine, Baltimore, USA.
Pellagra, a rare disorder caused by niacin deficiency, manifests as 4Ds: dermatitis, diarrhea, dementia, and, if left untreated, death. Though it was thought to be eradicated from the United States after fortification with niacin, there have been concerns about its reemergence in specific high-risk populations such as chronic alcoholism, malabsorption, and anorexia nervosa. Here we present a patient with altered mental status who subsequently developed diarrhea during the course of hospitalization.
View Article and Find Full Text PDFPellagra in chronic alcoholism: An underdiagnosed condition in modern clinical practice.
J R Coll Physicians Edinb
December 2024
Department of Dermatology & Venereology, Maulana Azad Medical College, New Delhi, Delhi, India.
Atypical presentation of pellagra with black urine: A clinical conundrum.
SAGE Open Med Case Rep
July 2024
University Medical Unit, Colombo South Teaching Hospital, Kalubowila, Sri Lanka.
Article Synopsis
- - Niacin (Vitamin B3) is vital for energy production, metabolism, and DNA repair, with severe deficiency leading to a condition called pellagra, which can cause dermatitis, dementia, diarrhea, and death if untreated.
- - A case involved a 68-year-old woman with symptoms like photosensitive dermatitis and abdominal pain, prompting diagnostic tests that ruled out porphyria cutanea tarda.
- - Ultimately, she was diagnosed with pellagra, and prompt treatment resulted in a complete recovery, highlighting the importance of timely diagnosis and management of this potentially fatal condition.
Case report: Pellagra presentation with dermatitis and dysphagia.
Front Med (Lausanne)
July 2024
School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Article Synopsis
- Pellagra is a disorder resulting from a lack of niacin or tryptophan, causing skin issues like dermatitis and gastrointestinal problems, including glossitis and diarrhea.
- Neurological symptoms can also arise, such as dementia and anxiety, but not all patients exhibit these.
- A case study discusses a woman who showed skin symptoms and difficulty swallowing without diarrhea or neurological signs; she was treated with niacin supplementation and recovered, underscoring the need for awareness in diagnosing pellagra based solely on skin and swallowing issues.
Roux-en-Y Gastric Bypass and the Clinical Manifestations of Vitamin Deficiencies: Case Report and Literature Review.
Cureus
March 2024
Infectious Diseases, Quillen College of Medicine at East Tennessee State University, Johnson City, USA.
Article Synopsis
- A 45-year-old female patient experienced serious complications after Roux-en-Y gastric bypass surgery (RYGBS), including weakness, hypotension, and inability to eat, leading to significant weight loss and bedridden status.
- She presented to the hospital with signs of dehydration and vitamin deficiencies, such as Pellagra and Bitot spots, as well as low protein and electrolyte imbalances.
- After being treated in the ICU and undergoing an endoscopy that revealed an anastomotic stricture, she was placed on Total Parenteral Nutrition (TPN) and discharged with education on vitamin supplementation and the importance of regular follow-up care.
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