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Implementing an obstetric sepsis bundle in a large academic hospital system.
Semin Perinatol
November 2024
Department of Clinical Informational Technology and Shared Services, New York-Presbyterian Hospital, New York, NY, United States.
For the purposes of this review, obstetric sepsis refers to sepsis (from all causes, including non-obstetric such as pneumonia) in pregnant or postpartum patients, which was previously described as maternal sepsis. Obstetric sepsis poses a significant threat to pregnant, birthing, and postpartum individuals, contributing prominently to maternal mortality and morbidity despite being largely preventable. In response to identified gaps in sepsis management, particularly the lack of specific protocols tailored to obstetric populations, New York-Presbyterian undertook a system-wide initiative to implement a comprehensive sepsis bundle.
View Article and Find Full Text PDFDrug utilization and medication adherence for the treatment of psoriatic arthritis: an Italian study.
Glob Reg Health Technol Assess
October 2024
Pescara General Hospital, Pescara - Italy.
Article Synopsis
- The study evaluates the use of biologic and targeted synthetic drugs for treating psoriatic arthritis (PsA) in Italy, specifically focusing on the role of biosimilar drugs.
- Conducted over four years at eight hospital pharmacies, the research tracked patients new to treatment, assessing their persistence and adherence to medication using the proportion of days covered (PDC).
- Findings revealed that patients on biosimilars showed better adherence and persistence than those on originators, and utilizing biosimilars resulted in significant cost savings, highlighting their potential benefits in healthcare resource optimization.
Consensus recommendations for acute trauma care & outcomes in LMICs from the transdisciplinary research, advocacy & implementation network for trauma in India.
Indian J Med Res
October 2024
The George Institute for Global Health, JPN Apex Trauma Center, New Delhi, India.
Background & objectives Injuries profoundly impact global health, with substantial deaths and disabilities, especially in low- and middle-income countries (LMICs). This paper presents strategic consensus from the Transdisciplinary Research, Advocacy, and Implementation Network for Trauma in India (TRAIN Trauma India) symposium, advocating for enhanced, system-level trauma care to address this challenge. Methods Five working groups conducted separate literature reviews on pre-hospital trauma care, in-hospital trauma resuscitation and training, trauma systems, trauma registries, and India's Towards Improving Trauma Care Outcomes (TITCO) registry.
View Article and Find Full Text PDFMRI findings and classification of brucella spondylitis: a China multicenter study.
Eur J Med Res
September 2024
Guangxi AIDS Clinical Treatment Center, The Fourth People's Hospital of Nanning, Nanning, People's Republic of China.
Article Synopsis
- - The study aims to create a standardized MRI classification for brucellosis spondylitis (BS) to improve treatment methods and post-treatment follow-up.
- - It analyzed data from 615 patients diagnosed with BS over 12 years, identifying key MRI characteristics and categorizing them into three main types, with Type II being the most common.
- - The findings suggest that using MRI features can enhance the diagnosis and treatment strategies for BS, providing a framework for ongoing patient management.
Managing unwarranted variation in hospital care - findings from a regional audit in Norway.
Res Health Serv Reg
November 2023
Southern and Eastern Norway Regional Health Authority, Parkgata 36, Hamar, 2317, Norway.
Background/aim: There has been increasing focus and research over the past decades on defining, identifying, visualizing and reducing unwarranted clinical variation in clinical practice. Both clinician-driven initiatives such as the US based "Choosing Wisely" campaign and the top-down driven "Evidence-based intervention programme (EBI)" launched by NHS UK to improve quality of care by reducing unnecessary interventions have shown marginal results. We present the findings from a mixed-methods audit performed to evaluate the compliance by senior hospital leaders of a new regional strategy to reduce unwarranted variation in outcomes and utilization rates.
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