AI Article Synopsis
- The study aimed to differentiate between ischemic cardiomyopathy (ICM) and nonischemic cardiomyopathy (NICM) using stress tests and gated SPECT imaging.
- Data from 145 patients with low left ventricular ejection fractions were analyzed, focusing on SPECT scores and exercise test results.
- Key findings suggest that higher summed stress scores, specific exercise metrics, and ST depression can effectively predict ICM, enhancing the overall diagnostic accuracy of SPECT imaging.
Article Abstract
Objective: Noninvasive differentiation between ischemic cardiomyopathy (ICM) and nonischemic (NICM) cardiomyopathy is frequently difficult. The aim of this study was to analyze the value of stress test and stress-rest gated single-photon emission computed tomography (SPECT) criteria to differentiate between ICM and NICM.
Methods: Data pertaining to 145 consecutive patients (mean age: 63±11 years, 24 women) assessed by means of stress-rest gated SPECT with Tc-tetrofosmin, with left ventricular ejection fraction less than or equal to 40% (107 patients with ICM and 38 with NICM according to coronary angiography) and known coronary anatomy, were analyzed.
Results: Multivariate analyses of gated SPECT variables identified a summed stress score greater than 21 [odds ratio (OR) 7.67, 95% confidence interval (CI): 2.85-20.58)] and divergent pattern (OR 6.84, 95% CI: 1.83-25.5) as predictors of ICM, and analysis of exercise test variables disclosed metabolic equivalents less than or equal to 7.3 (OR 10.75, 95% CI: 3.64-31.81) and ST depression of at least 1 mm (OR 6.97, 95% CI: 1.42-34.3) as independent predictors of ICM. The exercise test variables had a significant additional predictive value of ICM over gated SPECT variables (P<0.001).
Conclusion: Estimated functional capacity and ST depression improve the diagnostic value of stress-rest SPECT to differentiate between ICM and NICM.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/MNM.0b013e32835c08a4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identifying non-responders to cardiac resynchronization therapy in the non-left bundle branch block.
J Interv Card Electrophysiol
January 2025
Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1 Kishibe-Shimmachi, Suita, Osaka, 564-8565, Japan.
Background: Non-response to cardiac resynchronization therapy (CRT) is an important issue in the treatment of heart failure with reduced ejection fraction (HFrEF) and non-left bundle branch block (LBBB). Electrocardiogram-gated myocardial perfusion single-photon emission computed tomography imaging (G-MPI SPECT) is typically used to assess left ventricular (LV) dyssynchrony. This study aimed to determine whether G-MPI parameters are associated with non-responsiveness to CRT.
View Article and Find Full Text PDFUsefulness of dynamic perfusion SPECT with quantitative assessment of myocardial perfusion reserve for the detection of myocardial ischaemia in patients with presumed new left bundle branch block.
Eur Heart J Imaging Methods Pract
July 2024
Department of Nuclear Medicine, CHU de Caen Normandie, Normandie Univ, UNICAEN UR 4650 PSIR, Avenue Cote de Nacre, 14000 Caen, France.
Article Synopsis
- The study aimed to assess how well dynamic SPECT with quantitative analysis of myocardial blood flow (MBF) and myocardial flow reserve (MFR) can detect coronary artery disease (CAD) in patients with new left bundle branch block (LBBB).
- The evaluation involved 174 patients with LBBB, finding SPECT abnormalities in only a small percentage, and highlighting a correlation between reduced MFR and fixed defects, although only a few patients had significant CAD after further examination.
- The conclusion suggests that routine screening for CAD in patients with presumed new LBBB may not be necessary, given the low incidence of actual CAD found.
A survey of detection of Parkinson's disease using artificial intelligence models with multiple modalities and various data preprocessing techniques.
J Educ Health Promot
October 2024
Adani Institute of Infrastructure Engineering, Ahmedabad, Gujarat, India.
Parkinson's disease (PD) is a neurodegenerative brain disorder that causes symptoms such as tremors, sleeplessness, behavioral problems, sensory abnormalities, and impaired mobility, according to the World Health Organization (WHO). Artificial intelligence, machine learning (ML), and deep learning (DL) have been used in recent studies (2015-2023) to improve PD diagnosis by categorizing patients and healthy controls based on similar clinical presentations. This study investigates several datasets, modalities, and data preprocessing techniques from the collected data.
View Article and Find Full Text PDFClinical surveillance of split renal function in kidney transplant recipients using Tc-diethylenetriamine-pentaacetic acid (DTPA) dynamic renal scintigraphy: preliminary findings and novel insights.
Quant Imaging Med Surg
December 2024
Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Background: En bloc kidney transplantation (EBKT) involves transplantation of two kidneys, the aorta, and inferior vena cava from a deceased pediatric donor into an adult recipient. Recent articles have shown that EBKT is associated with excellent long-term allograft performance and patient survival. Developmental differences exist between the two transplanted kidneys after EBKT, and it is crucial to assess split renal function.
View Article and Find Full Text PDFSixteen-Frame Gated Myocardial Perfusion SPECT as a Surrogate for Equilibrium Radionuclide Angiography in Measurement of Systolic and Diastolic Indices: A Cross-Sectional Study.
World J Nucl Med
December 2024
Department of Nuclear Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Equilibrium radionuclide angiography (ERNA) has long been assumed as the preferred method to assess cardiac volumes as well as left ventricular systolic and diastolic indices. ERNA was used to diagnose subtle changes in cardiac function during chemotherapy or early stages of heart failure. Gated myocardial perfusion SPECT (GMPS) was introduced as a more feasible and versatile alternative to ERNA, but the precision of GMPS to assess systolic and diastolic indices has not yet been fully reviewed.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!