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Colchicine-induced rhabdomyolysis: a review of 83 cases.
BMJ Case Rep
July 2021
Internal Medicine, Wayne State University, Detroit, Michigan, USA
A 74-year-old man with medical history significant for atrial fibrillation, hyperlipidaemia and coronary artery disease on atorvastatin presented to the emergency department with profound weakness. The patient reports he first noticed his weakness 4 weeks after starting colchicine, prescribed for recurrent pericarditis with pericardial effusion, a complication following recent coronary artery bypass grafting. The patient was also on prednisone therapy for presumed post-pericardiotomy syndrome.
View Article and Find Full Text PDFColchicine-Induced Rhabdomyolysis: Clinical, Biochemical, and Neurophysiological Features and Review of the Literature.
Clin Med Insights Arthritis Musculoskelet Disord
June 2019
Servicio de Rehabilitación, Hospital Universitario Santa Cristina, Madrid, España.
We report the case of a 46-years-old man with long-term asymptomatic hyperuricemia who started taking colchicine (0.5 mg/day) and allopurinol (100 mg/d) for normalization of biochemical values. After the third week of starting treatment, acute weakness was present; and by the fifth week, profound weakness in lower extremities and tenderness and cramps on thighs and calves with inability to climb stairs were also observed.
View Article and Find Full Text PDFColchicine-Induced Rhabdomyolysis: An Autopsy Case.
Am J Forensic Med Pathol
June 2016
From the Council of Forensic Medicine, Istanbul, Turkey.
Colchicine is derived from Colchicum autumnale and Gloriosa superba and is used to treat acute gout and familial Mediterranean fever (FMF). Musculoskeletal adverse effects range from myopathy to rhabdomyolysis. An 18-year-old woman, with a 2-year history of FMF treated with colchicine, took 9 colchicine pills (4.
View Article and Find Full Text PDFColchicine-induced rhabdomyolysis following a concomitant use of clarithromycin in a haemodialysis patient with familial Mediterranean fever.
Clin Kidney J
December 2013
Department of Nephrology , Ankara University School of Medicine, Ankara , Turkey.
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