This paper evaluated the feasibility of using the horizontal radial plume mapping (HRPM) technique to locate multiple emission sources via computational simulation. Seventy-two test maps, each having two Gaussian distributions, were generated in a two-dimensional domain. The HRPM technique with the non-negative least square (NNLS) algorithm was then applied to reconstruct the plumes, assuming a nine-beam scanning beam geometry. The NNLS algorithm successfully reconstructed the source locations of 68 of the 72 test maps. However, when one of the plumes was near the origin, the NNLS did not always identify the peak locations correctly. Furthermore, when the two plumes were spaced closely, the NNLS tended to reconstruct a wide plume covering both plumes instead of separating them due to the resolution limitation of the current nine-beam geometry. In the sensitivity analysis, five sets of random error (1%, 5%, 10%, 20%, and 30%) were added in the path-integrated concentration (PIC) from the 72 test maps, and thus, an additional 360 reconstructions were implemented. Robust results were obtained when the noise added was less than 20%. The results generally support the implementation of the NNLS algorithm in the HRPM technique as described in the US. Environmental Agency (EPA) Other Test Method 10 (OTM-10).
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http://dx.doi.org/10.1080/10962247.2012.710552 | DOI Listing |
JAMIA Open
April 2024
Department of Obstetrics, Gynecology, and Reproductive Sciences at McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, United States.
Objective: High-risk pregnancy (HRP) conditions such as gestational diabetes mellitus (GDM), hypertension (HTN), and peripartum depression (PPD) affect maternal and neonatal health. Patient engagement is critical for effective HRP management (HRPM). While digital technologies and analytics hold promise, emerging research indicates limited and suboptimal support offered by the highly prevalent pregnancy digital solutions within the commercial marketplace.
View Article and Find Full Text PDFJ Pediatr Gastroenterol Nutr
April 2024
Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Objectives: Pharyngeal contractile integral (PhCI) is the product of mean pharyngeal contractile amplitude, length, and duration, and provides a single metric for the vigor of entire pharyngeal contraction. A major limitation in children is lack of characterization of PhCI on high-resolution pharyngeal manometry. We aimed to determine and compare the values of PhCI in children with the abnormal and normal videofluoroscopic study of swallow (VFSS).
View Article and Find Full Text PDFAm J Speech Lang Pathol
March 2024
Department of Otolaryngology-Head & Neck Surgery, Medical University of South Carolina, Charleston.
Purpose: The utilization of high-resolution pharyngeal manometry (HRPM) in the evaluation of pharyngeal dysphagia has been increasing; however, standardization of its use has lagged behind. Without standardization using normative values, it is difficult for clinicians to adopt this emerging technology into meaningful use. Our goal is to map and compare the published normative values for common HRPM metrics in order to help establish consensus reference values.
View Article and Find Full Text PDFGastroenterol Hepatol
March 2024
Unidad de Pruebas Funcionales Digestivas, Hospital de Mataró, Mataró, Barcelona, España; Centro de Investigación Biomédica en Red de enfermedades hepáticas y digestivas (CIBERehd), Instituto de Salud Carlos III, Barcelona, España. Electronic address:
Oropharyngeal dysphagia (OD) is a pathology with a high prevalence in different patient phenotypes. High-resolution pharyngoesophageal manometry (HRPM) with impedance (HRPM-I) has become in recent years a fundamental technique for better understanding the pathophysiology of pharynx and upper oesophageal sphincter (UES) dysfunctions in patients with OD. Various groups of experts have proposed a methodology for the practice of the HRPM-I and for the standardization of the different metrics for the study of pharyngeal motility and UES dysfunctions based on the quantification of 3main phenomena: relaxation of the UES, resistance to flow through the UES and propulsion of the bolo through the pharynx into the oesophagus.
View Article and Find Full Text PDFEvol Bioinform Online
October 2022
Department of Orthopaedics, Suzhou Hospital of Anhui Medical University, Suzhou, Anhui, China.
Background: Osteosarcoma (OS) is the most common malignant bone tumor in clinical practice, and currently, the ability to predict prognosis in the diagnosis of OS is limited. There is an urgent need to find new diagnostic methods and treatment strategies for OS.
Material And Methods: We downloaded the multi-omics data for OS from the TARGET database.
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