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The Beneficial Effects of Lactobacillus Strains on Gut Microbiome in Alzheimer's Disease: A Systematic Review.
Healthcare (Basel)
January 2025
Neuroimmunology Laboratory, School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.
Background/objectives: Growing evidence suggests that the gut-brain axis influences brain function, particularly the role of intestinal microbiota in modulating cognitive processes. Probiotics may alter brain function and behavior by modulating gut microbiota, with implications for neurodegenerative diseases like Alzheimer's disease (AD). The purpose of this review is to systematically review the current literature exploring the effects of probiotic supplementation on gut microbiota and cognitive function in AD and mild cognitive impairment (MCI).
View Article and Find Full Text PDFMechanical and optical properties of additively manufactured denture base resin in different colors modified with antimicrobial substances: An in vitro study.
J Prosthet Dent
January 2025
Associate Professor, Department of Restorative, Preventive and Pediatric Dentistry, School of Dental Medicine, University of Bern, Switzerland; and Adjunct Professor, Division of Restorative and Prosthetic Dentistry, The Ohio State University, Columbus, OH.
Statement Of Problem: Acrylic denture base resins are subject to colonization by oral and nonoral bacteria, contributing to the onset of denture stomatitis. However, how the addition of antimicrobial substances affects the mechanical and optical properties of additively manufactured denture base resin remains unclear.
Purpose: The purpose of this in vitro study was to investigate the surface roughness, color stainability, and flexural strength of antimicrobial-modified, additively manufactured polymethyl methacrylate (PMMA) denture base resin in tooth and gingiva colors.
Evaluating the diagnostic accuracy of fetal scalp blood sampling: A retrospective cohort study.
Eur J Obstet Gynecol Reprod Biol
December 2024
Maternal and Fetal Health Research Centre, Division of Developmental Biology and Medicine, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK; Saint Mary's Hospital, Manchester University NHS Foundation Trust, UK.
Introduction: Fetal scalp blood sampling (FSBS) can be used as an adjunctive test, in the presence of a pathological intrapartum fetal heart rate trace, to provide evidence of fetal acidaemia. The role of FSBS remains controversial, this study evaluates the diagnostic accuracy of FSBS at determining various adverse neonatal outcomes.
Method: A retrospective cohort analysis of FSBS undertaken < 1 h from birth in a single UK centre in 2016 and 2017.
Evaluation of an Orientation Program for Adjunct Clinical Instructors in Nursing.
Nurs Educ Perspect
October 2024
About the Authors Esther Gravis, DNP, RN, CPN, is assistant professor, University of Portland School of Nursing & Health Innovations, Portland, Oregon. Mary A. Dolansky, PhD, RN, FAAN, is Sarah C. Hirsh Professor, Frances Payne Bolton School of Nursing, and associate professor, School of Medicine, Case Western Reserve University, Cleveland, Ohio. For more information, contact Dr. Gravis at
Part-time clinical nurse instructors teach students in many nursing schools in the United States. They are often unprepared for this role and require instruction in teaching methods. We developed and evaluated an online orientation program to provide the knowledge and skills necessary for nurses to become confident clinical instructors.
View Article and Find Full Text PDFNeuroimmunometabolism: How Metabolism Orchestrates Immune Response in Healthy and Diseased Brain.
Am J Physiol Endocrinol Metab
January 2025
National Agri-Food and Biomanufacturing Institute (BRIC-NABI), Food & Nutrition Biotechnology Division, S.A.S Nagar, Sector 81 (Knowledge City), Punjab, India.
Neuroimmunometabolism describes how neuroimmune cells, such as microglia, adapt their intracellular metabolic pathways to alter their immune functions in the CNS. Emerging evidence indicates that neurons also orchestrate the microglia mediated immune response through neuro-immune crosstalk perhaps through metabolic signalling. However, little is known about how the brain's metabolic microenvironment and microglial intracellular metabolism orchestrate the neuroimmune response in healthy and diseased brains.
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