In this work we developed C(2)-symmetric chiral nucleophilic catalysts which possess a pyrrolidinopyridine framework as a catalytic site. Some of these organocatalysts effectively promoted asymmetric desymmetrization of meso-diols via enantioselective acylation.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511012 | PMC |
http://dx.doi.org/10.3762/bjoc.8.203 | DOI Listing |
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