Objectives: Recently, several studies have shown that a cochlear implant is a suitable treatment for hearing rehabilitation of adults with unilateral sensorineural hearing loss (UHL), and benefits for speech comprehension in noise and localization have been demonstrated. The aim of this clinical study was to evaluate the benefit of cochlear implantation in children with UHL in comparison to their unaided listening situation.
Study Design: Prospective repeated measures single subject design.
Setting: Tertiary referral center; cochlear implant (CI) program
Patients: Three children (4, 10, and 11 yr) with noncongenital UHL resulting from different causes were enrolled in the study.
Intervention: After extensive consultation with each family and confirming CI-candidacy, each child received a cochlear implant.
Main Outcome Measures: Open set speech recognition measures in competing background noise and tests of sound localization were performed for unaided preoperative and CI-aided postimplant intervals after 6 and 12 months. The parent and child versions of the Speech, Spatial and Qualities scale (SSQ) were used for subjective evaluation of hearing at preimplant and 12-month postimplant intervals.
Conclusion: All children consistently use their CI 1 year postimplant. Our preliminary results suggest binaural hearing benefits for speech understanding in noise, localization ability and subjectively perceived hearing ability for school-aged children with UHL. Trends for CI-benefits in younger preschoolaged children are confirmed through subjective assessment reported by the parents. The benefits in hearing performance suggest binaural integration and processing of electric and acoustic stimulation arriving at 2 different ears is possible for children with UHL.
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http://dx.doi.org/10.1097/MAO.0b013e31827850f0 | DOI Listing |
BMJ Glob Health
January 2025
Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.
Arch Dis Child Fetal Neonatal Ed
December 2024
Nuffield Department of Population Health, University of Oxford National Perinatal Epidemiology Unit, Oxford, UK.
Objective: Babies born between 27 and 31 weeks of gestation contribute substantially towards infant mortality and morbidity. In England, their care is delivered in maternity services colocated with highly specialised neonatal intensive care units (NICU) or less specialised local neonatal units (LNU). We investigated whether birth setting offered survival and/or morbidity advantages to inform National Health Service delivery.
View Article and Find Full Text PDFAnn Pediatr Cardiol
November 2024
Department of Pediatric Emergency, Sudden Infant Death Syndrome Liguria Centre, Istituto Giannina Gaslini, Genova, Italy.
Uhl's disease is a rare disorder secondary to the uncontrolled destruction of right ventricular myocytes during the perinatal period. We present here the case of a 1-month-old child who died suddenly of Uhl's disease, which was only diagnosed at autopsy and histological examination. From an anamnestic point of view, the child's sister had also died at about 1 month of age from the same pathology.
View Article and Find Full Text PDFClin Exp Allergy
November 2024
Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
Clin Radiol
September 2024
Department of Clinical Radiology, Great Ormond Street Hospital for Children, London, WC1H 3JH, UK; UCL Great Ormond Street Institute of Child Health, Great Ormond Street Hospital for Children, London, WC1N 1EH, UK; NIHR Great Ormond Street Hospital Biomedical Research Centre, 30 Guilford Street, Bloomsbury, London, WC1N 1EH, UK. Electronic address:
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