As an infrequent symptom diplopia has been reported with opiate withdrawal, especially heroin, but not dextropropoxyphene. We report incomitant esotropia and diplopia in a case with dextropropoxyphene withdrawal that resolved completely with the resolution of the opiate withdrawal syndrome.
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http://dx.doi.org/10.1016/j.genhosppsych.2012.10.009 | DOI Listing |
Fundam Clin Pharmacol
April 2024
INSERM, BPH, University of Bordeaux, Bordeaux, France.
Background: The combination dextropropoxyphene/paracetamol (DXP/P) was the most prescribed opioid analgesic until its withdrawal in 2011.
Objectives: This study investigated dispensations of analgesics in chronic users of DXP/P during the 18 months following its withdrawal.
Methods: A cross-sectional study repeated yearly was conducted by using the French reimbursement database from 2006 to 2015.
J Am Coll Cardiol
January 2021
Military Cardiovascular Outcomes Research, Cardiology Division, Uniformed Services University, Bethesda Maryland, USA.
Opioids are the most potent of all analgesics. Although traditionally used solely for acute self-limited conditions and palliation of severe cancer-associated pain, a movement to promote subjective pain (scale, 0 to 10) to the status of a "fifth vital sign" bolstered widespread prescribing for chronic, noncancer pain. This, coupled with rising misuse, initiated a surge in unintentional deaths, increased drug-associated acute coronary syndrome, and endocarditis.
View Article and Find Full Text PDFEur J Hosp Pharm
September 2020
Pharmaceutical Information Department, Centre Hospitalier Universitaire de Rennes, Rennes, France.
Objective: Pain management in the emergency department (ED) is a key issue that must be regularly evaluated. Practice evaluation gold standard remains patient file analysis, but is highly time consuming. The aim of this study is to evaluate the interest of a defined daily dose (DDD) based analysis in the evaluation of pain management in the ED.
View Article and Find Full Text PDFBr J Clin Pharmacol
February 2021
Centre d'addictovigilance, Service de pharmacologie médicale, CHU Bordeaux, Bordeaux, France.
Aims: Analgesics are the most widely used medicines worldwide. In parallel, opioid abuse has increased and is of major concern. The accessibility of pharmacologically powerful medicines and the addictovigilance signals in France about the risk of opiates addiction call for an overview of analgesic use.
View Article and Find Full Text PDFMed Care
January 2020
Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, Lebanon, NH.
Objective: Experts cautioned that patients affected by the November 2010 withdrawal of the opioid analgesic propoxyphene might receive riskier prescriptions. To explore this, we compared drug receipts and outcomes among propoxyphene users before and aftermarket withdrawal.
Study Design: Using OptumLabs data, we studied 3 populations: commercial, Medicare Advantage (MA) aged (age 65+ y) and MA disabled (age below 65 y) enrollees.
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