Pressure pain perception at the injured foot: the impact of diabetic neuropathy.

J Musculoskelet Neuronal Interact

Diabetic Foot Clinic, Department of Metabolic Diseases, Heinrich-Heine-University Düsseldorf, Germany.

Published: December 2012

Background: At feet with painless diabetic neuropathy (PDN) and a healed fracture (quiescent Charcot-foot), cutaneous pressure pain perception threshold (CPPPT) is elevated beyond the range of measurement, whereas deep pressure pain perception threshold (DPPPT) may be normal. It is unknown, how these thresholds behave under the conditions of a foot injury. We therefore measured CPPPT and DPPPT in the vicinity of a unilateral active foot injury.

Patients And Methods: 18 diabetic patients with PDN and plantar injury, partly involving the skeleton (Wagner grade I-II ulcer), 10 non-neuropathic subjects with acute painful skeletal injury (sprain, fracture) and 20 healthy control subjects without foot injury were studied. CPPPT was measured using calibrated monofilaments, and DPPPT was measured by Algometer II® over muscle and joint.

Results: Compared to control subjects, non-neuropathic acutely injured (and contralateral) feet displayed lowered CPPPT and DPPPT. Conversely, ulcerated and contralateral feet with PDN displayed unmeasurably elevated thresholds in 100% (CPPPT), 72% (DPPPT over joint), and 28% (DPPPT over muscle) of patients, respectively.

Conclusion: In the vicinity of an active foot injury, physiologic hyperalgesia was demonstrated in the non-neuropathic subjects, but not in the patients with PDN in whom neglect of foot trauma is, therefore, common.

Download full-text PDF

Source

Publication Analysis

Top Keywords

pressure pain
12
pain perception
12
foot injury
12
diabetic neuropathy
8
perception threshold
8
cpppt dpppt
8
active foot
8
patients pdn
8
non-neuropathic subjects
8
control subjects
8

Similar Publications

Purpose: To analyze available evidence in the literature on the effect of aromatherapy for the management of postoperative pain in the postanesthesia care unit (PACU).

Design: Systematic review according to the Joanna Briggs Institute (JBI) model and Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement.

Methods: The search was carried out in August 2023, using descriptors and keywords, in the Cumulative Index to Nursing and Allied Health Literature, Latin American and Caribbean Literature in Health Sciences, Cochrane Central Register of Controlled Trials, Excerpta Medica Database, PUBMED, Scopus, Virtual Health Library, Google Scholar, CAPES, BDTD, and ProQuest portals of theses and dissertations, with no language restrictions or time limit.

View Article and Find Full Text PDF

Background: Non-specific chronic neck pain is a prevalent musculoskeletal disorder with a significant impact on individuals' quality of life. The lack of consensus on effective therapeutic management complicates the establishment of standardized treatment protocols. Home exercise programs have yielded positive results.

View Article and Find Full Text PDF

Boosting Recovery: Omega-3 and Whey Protein Enhance Strength and Ease Muscle Soreness in Female Futsal Players.

Nutrients

December 2024

Department of Administration and Curriculum, Program of Sports Management and Training, Faculty of Arts and Educational Sciences, Middle East University, Amman 11831, Jordan.

Adequate nutrition is crucial for athletes to enhance performance and recovery. This study investigates the acute effects of omega-3 and whey protein supplementation before and after exercise-induced muscle damage (EIMD) on lower-body strength, explosive power, and delayed-onset muscle soreness (DOMS) in female futsal players. A randomized, cross-over, placebo-controlled, double-blind study involved 15 female futsal players (Age: 22.

View Article and Find Full Text PDF

Randomized Clinical Evaluation of the Healing Activity of Green Propolis Ointment in Individuals with Lower Limb Ulcers Resulting from Leprosy: Preliminary Results of a Pilot Study.

Pharmaceuticals (Basel)

December 2024

Laboratory of Molecular Pharmacology and Bioactive Compounds, Postgraduate Program in Health Sciences, São Francisco University, 215 São Francisco de Assis Avenue, Bragança Paulista 12916-900, São Paulo, Brazil.

Treating chronic wounds incurs substantial costs for Brazil's Unified Health System. Natural compounds, particularly propolis, are increasingly explored as low-cost alternatives due to their healing properties. Brazilian green propolis, distinct in its chemical composition, has garnered scientific interest.

View Article and Find Full Text PDF

: Autonomic nervous system (ANS) disorders are responsible for primary dysmenorrhea and are closely linked to the spine. This study aims to evaluate the effects of sacroiliac joint manipulation on the ANS and lower abdominal pain in women with primary dysmenorrhea and proposes an alternative treatment method. : A total of 40 participants were randomly assigned; however, 35 participants remained in the final analysis after 5 dropped out; they were assigned to either the sacroiliac joint manipulation group ( = 18) or the superficial heat therapy group ( = 17).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!