Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.amepre.2012.09.009 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Classification-based pathway analysis using GPNet with novel P-value computation.
Brief Bioinform
November 2024
Center for Artificial Intelligence Research, Wake Forest University School of Medicine, Winston-Salem, NC 27101, United States.
Pathway analysis plays a critical role in bioinformatics, enabling researchers to identify biological pathways associated with various conditions by analyzing gene expression data. However, the rise of large, multi-center datasets has highlighted limitations in traditional methods like Over-Representation Analysis (ORA) and Functional Class Scoring (FCS), which struggle with low signal-to-noise ratios (SNR) and large sample sizes. To tackle these challenges, we use a deep learning-based classification method, Gene PointNet, and a novel $P$-value computation approach leveraging the confusion matrix to address pathway analysis tasks.
View Article and Find Full Text PDFExperiences of Nurse Managers in the 2023 Kahramanmaras, Turkey Earthquakes: A Qualitative Study.
J Trauma Nurs
January 2025
Author Affiliations: Department of Management and Organization, Bayburt University, Bayburt, Turkey (Dr Koroglu Kaba); Akdağmadeni School of Health, Yozgat Bozok University, Yozgat, Turkey (Dr Bal); and Nursing Department, Faculty of Health Sciences, Karadeniz Technical University, Trabzon, Turkey (Dr Ozturk).
Background: Nurse managers play a critical role in disaster response and management; yet research on their experiences in earthquakes remains limited.
Objective: This study aimed to explore the experiences of nurse managers in the Kahramanmaras, Turkey, earthquakes.
Methods: A phenomenological approach was used to guide this study, exploring the lived experiences of nurse managers who worked during the 2023 earthquakes in Kahramanmaras, Turkey.
Serine phosphorylation facilitates protein degradation by the human mitochondrial ClpXP protease.
Proc Natl Acad Sci U S A
February 2025
Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
ClpXP is a two-component mitochondrial matrix protease. The caseinolytic mitochondrial matrix peptidase chaperone subunit X (ClpX) recognizes and translocates protein substrates into the degradation chamber of the caseinolytic protease P (ClpP) for proteolysis. ClpXP degrades damaged respiratory chain proteins and is necessary for cancer cell survival.
View Article and Find Full Text PDFThe Critical Role of Commercial Analytical Reference Standards in the Control of Chemical Risks: The Case of PFAS and Ways Forward.
Environ Health Perspect
January 2025
Department of Environmental Health, Boston University School of Public Health, Boston, Massachusetts, USA.
Background: Various countries have instituted risk governance measures to control and minimize the risks of chemicals at the national and international levels. Activities typically include risk assessment based on ) hazard and exposure assessments; ) setting limits on the production, use, and emissions of chemicals; ) enforcement of regulations; and ) monitoring the effectiveness of the measures taken. These steps largely depend on chemical analysis and access to pure chemical reference standards.
View Article and Find Full Text PDFA short screen for lifetime sexual victimization experiences: Expanding research on the Sexual Abuse History Questionnaire (SAHQ) across cultures, genders, and sexual identities.
Int J Clin Health Psychol
January 2025
Département de Psychologie, Université de Montréal, Montréal, Canada.
The Sexual Abuse History Questionnaire (SAHQ), a widely used screening tool for childhood sexual abuse (CSA) and adolescent/adult sexual assault (AASA) experiences, has limited examination of its psychometric properties in diverse populations. Our study assessed the SAHQ's psychometric properties (i.e.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!