Follicle flushing in monofollicular in vitro fertilization almost doubles the number of transferable embryos.

Acta Obstet Gynecol Scand

Department of Gynecological Endocrinology and Reproductive Medicine, University Women's Hospital, Effingerstrasse 102, Bern, Switzerland.

Published: March 2013

AI Article Synopsis

  • Follicle flushing has been shown to be ineffective in polyfollicular in vitro fertilization, but its effect in monofollicular cases was analyzed with 164 cycles.
  • The study found that oocyte yield increased significantly from flushing, with a total yield rising from 44.5% to 80.5% after the procedure.
  • Additionally, the transfer rate of viable embryos improved significantly from 20.1% to 38.4%, demonstrating that flushing can enhance oocyte and embryo outcomes.

Article Abstract

Follicle flushing has been proved to be ineffective in polyfollicular in vitro fertilization. To analyze the effect of flushing in monofollicular in vitro fertilization we aspirated and then flushed the follicles in 164 cycles. Total oocyte yield/aspiration was 44.5% in the aspirate, 20.7% in the 1(st) flush, 10.4% in the 2(nd) flush and 4.3% in the 3(rd) flush. By flushing, the total oocyte yield increased (p < 0.01) by 80.9%, from 44.5 to 80.5%. The total transfer rate increased (p < 0.01) by 91.0%, from 20.1 to 38.4%. The results indicate that the oocyte yield and the number of transferable embryos can be increased significantly by flushing.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596803PMC
http://dx.doi.org/10.1111/aogs.12054DOI Listing

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