Purpose: To estimate the prevalence of self-reported "sensitive eyes" (SEs) in soft contact lens (CL) wearers, evaluate the clinical characteristics of patients with SEs, and examine the effect of refitting them with silicone hydrogel lenses.
Methods: After self-assessment, 2154 CL wearers were separated into SE and non-SE patients. Demographics, biometric data, wearing time, symptoms, and signs were compared between the two populations. Sixty-three SE patients were randomized into senofilcon A (senA) lenses and 65 into a non-senA arm (lotrafilcon B, omafilcon A, and balafilcon A lenses). The performance of senA lenses was compared against habitual and non-senA lenses 2 weeks later.
Results: A total of 12.2% of CL wearers reported SEs with their habitual CLs. No significant differences were noticed between SE and non-SE patients in sex, age, or refraction. The prevalence of dryness (43 vs 19%, p < 0.0001), irritation (25 vs 11%, p < 0.0001), redness (20 vs 6%, p < 0.0001), and stinging (6 vs 1%, p < 0.0001) was higher in SE patients. Average wearing time (13.0 vs 14.1 hours, p < 0.0001) was lower in this group. Limbal/bulbar hyperemia and corneal/conjunctival staining were not significantly different between the two populations. Senofilcon A increased the number of patients reporting no dryness (habitual vs senA, 20 vs 44%, p < 0.0003), irritation (22 vs 37%, p = 0.015), redness (52 vs 76%, p =0.009) and stinging (58 vs 77%, p = 0.012) but did not significantly affect clinical signs. Senofilcon A was significantly more efficient than non-senA lenses in improving dryness (scale of 0 to 3: senA vs non-senA, 0.64 vs 1.02, p = 0.0056), irritation (0.72 vs 1.16, p = 0.0015), and stinging (0.18 vs 0.53, p = 0.0049).
Conclusions: A substantial proportion of CL wearers report SEs with their habitual lenses. These patients are characterized by a high prevalence of additional symptoms, which are not reflected in clinical signs. Senofilcon A, or lenses with similar properties, may help reduce these symptoms in SE patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/OPX.0b013e3182775c78 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Repeatability of lipid layer thickness using LipiView® following removal of contact lenses and its relationship to comfort.
Ophthalmic Physiol Opt
January 2025
School of Optometry and Vision Science, University of New South Wales, Sydney, New South Wales, Australia.
Purpose: To assess the repeatability of lipid layer thickness (LLT) measurement using the LipiView® interferometer after daily disposable contact lens (CL) wear and correlation with ocular comfort in soft contact lens wearers.
Methods: A prospective study was conducted over two consecutive months, wherein CL wearers (n = 20) wore either Somofilcon A or Verofilcon A daily disposable CLs in a crossover design, switching lenses after 1 month. The pre-corneal tear film LLT was measured at the end of each month after CLs had been worn for at least 6 h.
Liquid-infused nanostructured composite as a high-performance thermal interface material for effective cooling.
Nat Commun
January 2025
Department of Mechanical Engineering, Carnegie Mellon University, 5000 Forbes Ave, Pittsburgh, PA, USA.
Effective heat dissipation remains a grand challenge for energy-dense devices and systems. As heterogeneous integration becomes increasingly inevitable in electronics, thermal resistance at interfaces has emerged as a critical bottleneck for thermal management. However, existing thermal interface solutions are constrained by either high thermal resistance or poor reliability.
View Article and Find Full Text PDFImportance: For myopia control to be beneficial, it would be important that the benefit of treatment (slowed eye growth) is not lost because of faster than normal growth (rebound) after discontinuing treatment.
Objective: To determine whether there is a loss of treatment effect (rebound) after discontinuing soft multifocal contact lenses in children with myopia.
Design, Setting, And Participants: The Bifocal Lenses in Nearsighted Kids 2 (BLINK2) cohort study involved children with myopia (aged 11-17 years at BLINK2 baseline) who completed the BLINK Study randomized clinical trial.
Uncertainty analysis in river quality management considering failure probability: controllable and uncontrollable input pollutants.
Ecotoxicol Environ Saf
January 2025
Chair of Engineering Hydrology and Water Management, Technical University of Darmstadt, Darmstadt, Germany. Electronic address:
River quality management involves complex challenges due to inherent uncertainties in various parameters, especially when dealing with controllable and uncontrollable pollutants. This study integrates a finite volume approach, called SEF (symmetric exponential function), with Monte Carlo simulations in MATLAB to solve the advection-dispersion equation, focusing on evaluating river quality protection tools by considering failure probability (P). Critical specifications for maintaining reliable river ecosystem performance are identified.
View Article and Find Full Text PDFDevelopment of an antimicrobial tissue conditioner with quaternary ammonium methacryloxy silane (K18): An in vitro study.
J Prosthodont Res
January 2025
Department of Comprehensive Dentistry, UT Health San Antonio, San Antonio, USA.
Purpose: To determine the effects of K18 quaternary ammonium methacryloxy silane (QAS) on tissue conditioner materials and their antimicrobial properties.
Methods: 30% K18 QAS in methyl methacrylate (MMA; K18-MMA; 0%, 15%, and 20% w/w) was incorporated into a commercial tissue conditioner (Coe comfort). The degree of curing (Shore A hardness), hydrophilicity (contact angle), flow, liquid sorption, mass loss, and antimicrobial properties of Streptococcus mutans, Streptococcus sanguinis, and Candida albicans were determined.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!