The influence of substitute materials on bone density after maxillary sinus augmentation: a microcomputed tomography study.

Purpose: To evaluate whether adding bone substitute materials to autogenous particulated bone (PAB) might have an effect on the density of the grafted bone after maxillary sinus augmentation.

Materials And Methods: Thirty healthy patients undergoing lateral antrostomy were included. Sinuses were augmented at random with PAB (n=10) (control group); a mixture of PAB and beta-tricalcium phosphate (Β-TCP) (n=10) (experimental group); or a mixture of PAB, Β-TCP, and hydroxyapatite (HA) (n=10) (experimental group). A sample of each graft material was obtained at time of maxillary sinus augmentation, and microcomputed tomography (Μ-CT) analyses were performed. Five months later, samples of the augmented areas (n=23) were harvested by means of a trephine bur, and Μ-CT analyses of these samples were performed. Density values for the bone were compared to the data obtained 5 months before from the original material.

Results: All groups showed increasing density values after a healing time of 5 months. Because of a high dropout rate, the sample size was too small to compare the groups statistically.

Conclusions: Bone density increased after maxillary sinus augmentation for both PAB alone or in combination with substitute materials based on HA and/or Β-TCP particles. A larger sample size and a split-mouth design would help to reliably reveal significant differences between the single materials.