Choledocholithiasis presenting with very high transaminase level.

BMJ Case Rep

Department of Specialist Medicine, Queen Elizabeth Hospital, London, UK.

Published: November 2012

We present three cases of choledocholithiasis presenting with a rise in transaminase to levels normally associated with acute hepatitis (alanine aminotransferase in excess of 1000 IU/l). All three cases had repeated investigation for liver disease before identification of common bile duct stones with magnetic resonance cholangiopancreatogram, and removal at endoscopic retrograde cholangiopancreatogram. We discuss the existing literature and the potential mechanisms of hepatocyte injury in extrahepatic obstruction.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543834PMC
http://dx.doi.org/10.1136/bcr-2012-007268DOI Listing

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