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Bronchiolitis Obliterans Organizing Pneumonia After Breast Radiation Therapy.
Pract Radiat Oncol
November 2024
Department of Advanced Biomedical Sciences, University Federico II, Napoli, Italy.
Presented here is a case report of a 77-year-old woman affected by rheumatoid arthritis who underwent breast-conserving surgery followed by radiation therapy (RT) for left-breast cancer and developed bronchiolitis obliterans organizing pneumonia (BOOP) after RT and during a COVID-19 vaccination campaign. BOOP incidence is an uncommon morbidity after breast RT (1.2%-2.
View Article and Find Full Text PDFReversed halo sign in radiation induced organizing pneumonia: natural course of the underlying pathophysiology.
Pulmonology
March 2022
Interstital Lung Disease Unit, Athens Medical Center, Athens, Greece; First Academic Department of Pneumonology, Hospital for Diseases of the Chest, "Sotiria", Medical School, National and Kapodistrian University of Athens, Greece. Electronic address:
Urgent lung transplantation for thymic neoplasm-associated severe constrictive bronchiolitis with bronchiectasis and radiotherapy-induced organizing pneumonia: A case report.
Thorac Cancer
June 2021
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Here, we present the case of a 28-year-old woman who developed severe and progressive thymoma-associated constrictive bronchiolitis with bronchiectasis, despite undergoing thymectomy. The disease was further complicated by radiation-induced organizing pneumonia (RIOP), which developed after adjuvant radiotherapy (RT) for Masaoka stage II thymoma. The patient was successfully treated with an urgent lung transplantation (LTx) for irreversible respiratory failure.
View Article and Find Full Text PDFAre there overlapping clinical features between thoracic radiotherapy side effects and covid-19 pneumonia? Radiation pneumonitis outside the radiation ports: Three case reports.
Clin Transl Radiat Oncol
November 2020
Radiation Oncology Unit, San Giuseppe Moscati Hospital, Strada per Martina Franca 74100, Taranto, Italy.
Respiratory involvement of COVID-19 infection, with presentations ranging from a mild flu-like illness to potentially lethal acute respiratory distress syndrome, is the main clinical manifestation in adults. Chest imaging shows a pictorial fashion of images due to the severity and stage of the disease, starting from focal nodular or mass-like opacities with air bronchogram to areas of ground glass consolidation or whited out lung. However, during the COVID-19 pandemic, CT findings could yield confounding reporting in the case of cancer patients previously treated with thoracic radiotherapy (tRT) due to atypical radiation pneumonitis occurring outside the radiation ports.
View Article and Find Full Text PDF[Medical prevention and treatment of radiation-induced pulmonary complications].
Cancer Radiother
August 2017
Département de radiothérapie, Gustave-Roussy cancer campus, 114, rue Édouard-Vaillant, 94805 Villejuif, France; Inserm, U1030, 114, rue Édouard-Vaillant, 94805 Villejuif, France; Université Paris Sud université Paris-Saclay, 78, avenue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France; Institut de recherche biomédicale des armées, D19, 91220 Brétigny-sur-Orge, France; École du Val-de-Grâce, 1, place Alphonse-Laveran, 75230 Paris cedex 05, France. Electronic address:
Radiation-induced lung injuries mainly include the (acute or sub-acute) radiation pneumonitis, the lung fibrosis and the bronchiolitis obliterans organizing pneumonia (BOOP). The present review aims at describing the diagnostic process, the current physiopathological knowledge, and the available (non dosimetric) preventive and curative treatments. Radiation-induced lung injury is a diagnosis of exclusion, since clinical, radiological, or biological pathognomonic evidences do not exist.
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