Nat Prod Res
a College of Food and Bioengineering , Henan University of Science and Technology, Luoyang , 471003 , China.
Published: April 2014
The purpose of this study was to evaluate the sedative and hypnotic effects of Eucommiol, a monomer compound extracted from male Eucommia flowers using a system solvent method. Eucommiol shows significant effects in mice, including reduced spontaneous activity, and increased the sleep ratio or lengthened the sleep time with a subthreshold or superthreshold dose of pentobarbital sodium, respectively. In addition, could effectively shorten sleep latency, reduce convulsion rate and prolong convulsion latency. These findings intensely indicated that Eucommiol has excellent sedative and hypnotic effects.
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http://dx.doi.org/10.1080/14786419.2012.746343 | DOI Listing |
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