Cellular hydrogel biopaper for patterned 3D cell culture and modular tissue reconstruction.

Adv Healthc Mater

Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea.

Published: September 2012

AI Article Synopsis

  • Researchers have developed a new type of biopaper made from cellular hydrogels that can be used for 3D cell culture and tissue reconstruction.
  • This biopaper incorporates innovative techniques for harvesting, transferring, and assembling tissue components, leading to the creation of laminated tissue composites.
  • An example of this application is the hepatic hydrogel sheets, which enhance liver functionality and are intended for creating layered 3D liver tissues.

Article Abstract

Microarchitectured freestanding cellular hydrogel biopaper as a novel 3D cell culture or tissue reconstruction module is reported. New harvesting, transfer, and assembly techniques are used to construct laminated tissue composites of the biopaper, such as hepatic hydrogel sheet modules with augmented liver function for stratified 3D hepatic tissue reconstruction.

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Source
http://dx.doi.org/10.1002/adhm.201200158DOI Listing

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