AI Article Synopsis
- This report highlights a rare case of acute adult T-cell leukemia/lymphoma (ATL) in a young girl who initially had infective dermatitis linked to HTLV-1.
- The girl’s condition progressed from dermatitis to ATL, marked by specific genetic tests (Southern blot hybridization and gamma-TCR rearrangement) indicating a monoclonal pattern.
- This study is significant because it adds to the limited cases of ATL in young patients, emphasizing the connection between HTLV-1 infection and the development of leukemia.
Article Abstract
Few cases of acute adult T-cell leukemia/lymphoma (ATL) have been diagnosed in young patients. This report is the first to describe a young girl with infective dermatitis associated with HTLV-1 that progressed to acute ATL with Southern blot hybridization and gamma-TCR-rearrangement revealing a monoclonal pattern with two copies of the provirus.
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| http://dx.doi.org/10.1016/j.jcv.2012.10.010 | DOI Listing |
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